STUDIES ON THEILERIOSIS IN CROSSBRED CALVES BEFORE AND AFTER TREATMENT BY BUPARVA-QUONE UNDER THE EFFECT OF LOCAL CONDITIONS IN UPPER EGYPT | ||||
Kafrelsheikh Veterinary Medical Journal | ||||
Article 3, Volume 1, Issue 2, October 2003, Page 29-46 PDF (902.42 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/kvmj.2003.112302 | ||||
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Authors | ||||
M. Abdel-Salam* 1; M. W. Ghattas2 | ||||
1Animal Health Research Institute, Port Said Regional Laboratory. | ||||
2Animal Health Research Institute, Port Said Regional Laboratory | ||||
Abstract | ||||
Thisstudyaimed toestimatethe drastic effects of Theileria annulata infectiononthegeneral health condition and some haematological and biochemical parameters and to evaluate the efficacy of Buparvaquone in treatment of crossbred calves.Bup-arvaquonewas injected atadose rate of 2.5 mg/kg BW as a single dose (group A) or double doses with 48 h intervals(group B).The rate of Parasitaemia in the infectedcalves reached12-28 %.Pyre-xia reached 40.5-41.3 °C.Anaemia was a hall-mark of the disease accompanied by reduction of the mean values of blood serum total protein, albumin, globulin, glucose, cholesterol, calcium, and phosphorous while non significant changes in the conce-ntrations of blood serum triglycerides and magnesium were recorded if compared to the non infected control calves (group C). Animals in group A showed elevated rectal temperature (40-40.6 °C) for 5-8 days and the rate of parasitaemia declined slowly till it reached its minimal level (4.5 %) 20 deys post treatment (PT). Also, 2 calves were died at the day7and8PT with high rate of parasitaemia(33-41%)and pyrexia (41.6°C). In group B, the temperature subsided 1-2 days after the 2nd dose and the rate of parasitaemia reached to less than 1% at the day 12.Haematological parameters remained reduced PT in group < /em>A,while theyrestoredtheirnormalvaluesexcept total leucocytic count in group B. Biochemical parameters were restored except serum globulin conc-entrationingroup < /em>B,whihremaindingroup < /em>A.From theseinvestigations we can concluded that buparvaquone at a dose rate 2.5 mg/kg BW in double dose with 48 h intervals is more efficient than a single dose under the local environment of Upper Egypt. | ||||
Keywords | ||||
Theileria annulata; Buparvaquone; crossbred calves | ||||
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