Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis (SREAT): A Case Report | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 12, Volume 81, Issue 1, October 2020, Page 1231-1233 PDF (458.03 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2020.112309 | ||||
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| Author | ||||
| Hessah Abdulaziz Al Hussaini | ||||
| Department of Internal Medicine, College of Medicine, King Faisal University, Al Ahsa, Kingdom of Saudi Arabia | ||||
| Abstract | ||||
| Background: Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT), also known as Hashimoto’s encephalopathy, is a disorder characterized by an encephalopathy associated with anti-thyroid antibodies in the absence of alternative causes. It has a wide range of clinical, laboratory and radiological features. Objective: Cases of steroid-responsive encephalopathy associated with autoimmune thyroiditis are difficult to diagnose and requires a high index of suspicion, as this will determine the early timing of management and disease outcome. Patient and Methods: Here we present a case report of twenty-year-old woman presenting with neurological and psychological symptoms. She was found to have high anti-thyroid peroxidase antibodies (Anti-TPO) with normal thyroid function and negative screening for other etiologies of encephalopathy. Based on her presentation, she was diagnosed with steroid-responsive encephalopathy associated with autoimmune thyroiditis. Results: Patient was started on high dose steroids upon which she responded partially. Then she required the addition of immunotherapy in the form of Rituximab to improve her symptoms. Conclusion: After exclusion of other causes of encephalopathy, the presence of thyroid antibodies prompts the susp < /span>icion of SREAT and therefore the early initiation of steroids to improve patients’ outcome. | ||||
| Keywords | ||||
| Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis; SREAT; Hashimoto’s encephalopathy; Encephalopathy; Autoimmune thyroiditis | ||||
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