PHARMACOLOGICAL STUDY ON THE EFFECT OF DICLAZURIL AND FLAVOMYCIN ON THE IMMUNE RESPONSE IN CHICKENS
Abdel-Aziz, M., Zahra, A., El-Seedi, I., Abdel-Hafez, G. (2005). PHARMACOLOGICAL STUDY ON THE EFFECT OF DICLAZURIL AND FLAVOMYCIN ON THE IMMUNE RESPONSE IN CHICKENS. EKB Journal Management System, 3(1), 115-134. doi: 10.21608/kvmj.2005.112450
M.I Abdel-Aziz; A.A. Zahra; I.A. El-Seedi; Ghada Abdel-Hafez. "PHARMACOLOGICAL STUDY ON THE EFFECT OF DICLAZURIL AND FLAVOMYCIN ON THE IMMUNE RESPONSE IN CHICKENS". EKB Journal Management System, 3, 1, 2005, 115-134. doi: 10.21608/kvmj.2005.112450
Abdel-Aziz, M., Zahra, A., El-Seedi, I., Abdel-Hafez, G. (2005). 'PHARMACOLOGICAL STUDY ON THE EFFECT OF DICLAZURIL AND FLAVOMYCIN ON THE IMMUNE RESPONSE IN CHICKENS', EKB Journal Management System, 3(1), pp. 115-134. doi: 10.21608/kvmj.2005.112450
Abdel-Aziz, M., Zahra, A., El-Seedi, I., Abdel-Hafez, G. PHARMACOLOGICAL STUDY ON THE EFFECT OF DICLAZURIL AND FLAVOMYCIN ON THE IMMUNE RESPONSE IN CHICKENS. EKB Journal Management System, 2005; 3(1): 115-134. doi: 10.21608/kvmj.2005.112450

PHARMACOLOGICAL STUDY ON THE EFFECT OF DICLAZURIL AND FLAVOMYCIN ON THE IMMUNE RESPONSE IN CHICKENS

Kafrelsheikh Veterinary Medical Journal
Article 9, Volume 3, Issue 1, April 2005, Page 115-134  XML PDF (798.23 K)
Document Type: Original Article
DOI: 10.21608/kvmj.2005.112450
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Authors
M.I Abdel-Aziz* 1; A.A. Zahra1; I.A. El-Seedi2; Ghada Abdel-Hafez2
1Pharmacology Dep., Fac. of Vet. Med., Tanta University (Kafr El-Sheikh)
2Animal Health Research Institute, El-Dokki, Giza
Abstract
The present study was conducted to evaluate diclazuril at the recommended and its two folds doses (1 & 2 ppm), flavomycin at 75 gm/ton and their combinations on the immune response in chickens vaccinated with IBD vaccine. Diclazuril displayed a dose dependent immunity suppression. In the recommended dose, it did not harm the bird immunity. While, in double recommended dose, it significantly suppressed the chicken immune response to IBD virus vaccine. The depressed response was reflected as a decreased bursal weight, skin hypersensitivity, total leucocytic count, lymphocyte count, antibody titer, serum protein and  serum globulins. While, flavomycin at 75 gm/ton had no detectable effect on the bird immune response to IBD virus vaccine. The combinations between diclazuril (as an anticoccidial drug) and flavomycin (as a growth promotor) have no drug interaction in our experiment.
Keywords
DICLAZURIL; FLAVOMYCIN; IMMUNE RESPONSE; CHICKENS
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