Oncological Outcomes and Safety of Ovarian Preservation in Early Stage Carcinoma of the Cervix
Badr, M., Elnemr, A., Alattar, A., Alabiad, M., Osman, G., El-Taher, A. (2022). Oncological Outcomes and Safety of Ovarian Preservation in Early Stage Carcinoma of the Cervix. EKB Journal Management System, 28(5), 1009-1015. doi: 10.21608/zumj.2020.38315.1915
Mohammad Samir Badr; Amr Abmohsen Elnemr; Ahmed Z Alattar; Mohamed Ali Alabiad; Gamal Osman; Ahmed K El-Taher. "Oncological Outcomes and Safety of Ovarian Preservation in Early Stage Carcinoma of the Cervix". EKB Journal Management System, 28, 5, 2022, 1009-1015. doi: 10.21608/zumj.2020.38315.1915
Badr, M., Elnemr, A., Alattar, A., Alabiad, M., Osman, G., El-Taher, A. (2022). 'Oncological Outcomes and Safety of Ovarian Preservation in Early Stage Carcinoma of the Cervix', EKB Journal Management System, 28(5), pp. 1009-1015. doi: 10.21608/zumj.2020.38315.1915
Badr, M., Elnemr, A., Alattar, A., Alabiad, M., Osman, G., El-Taher, A. Oncological Outcomes and Safety of Ovarian Preservation in Early Stage Carcinoma of the Cervix. EKB Journal Management System, 2022; 28(5): 1009-1015. doi: 10.21608/zumj.2020.38315.1915

Oncological Outcomes and Safety of Ovarian Preservation in Early Stage Carcinoma of the Cervix

Zagazig University Medical Journal
Article 13, Volume 28, Issue 5, September 2022, Page 1009-1015  XML PDF (555.71 K)
Document Type: Original Article
DOI: 10.21608/zumj.2020.38315.1915
View on SCiNiTO View on SCiNiTO
Authors
Mohammad Samir Badr1; Amr Abmohsen Elnemr2; Ahmed Z Alattar3; Mohamed Ali Alabiad email orcid 4; Gamal Osman5; Ahmed K El-Taher5
1Department of Gynecology and Obstetrics, Zagazig University Faculty of Medicine, Zagazig, Egypt
2gynecology and Obstetrics Department, Faculty of medicine, Zagazig University.
3Department of Clinical Oncology and Nuclear Medicine, Zagazig University Faculty of Medicine, Zagazig, Egypt
4Pathology Department, Faculty of Medicine, Zagazig University
5Department of General surgery, Faculty of Medicine, Zagazig University Zagazig, Egypt
Abstract
Conservative ovarian management plans for young patients having cervical cancer is now widely accepted, Preservation of one or both ovaries in patients with cervical adenocarcinoma is still a controversial issue but preservation of the ovaries in patients with certain criteria might be considered more important to those patients having cancer cervix who were diagnosed in the early stage.So it is important to establish the selection criteria of cervical cancer patients who will be eligible for preservation of ovarian function.The aim of our study was to identify suitable cervical cancer patients who will benefit from preservation of their ovaries and to detect the survival benefits and patients outcome.Patients and methods: Performing the current prospective cohort study was done in the period from September2014to October2019.We included60females with cancer cervix stage(I-II),we divided patients into two groups the first group included30females underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy and the second group included30patients and underwent total abdominal hysterectomy with preservation of the ovaries.We followed the patients for5years.Results:we showed that patients with preserved ovaries were younger, with lower T stage,earlier(FIGO)stage(IA-B),ower histological grades.Five-year cancer specific survival-rate was higher in the ovarian conservation group than in the oophorectomy group, OS-rate was higher in the ovarian conservation group than in the oophorectomy group.Conclusion:Our study showed that preservation of ovaries in in young females patients who diagnosed with early stage cervical carcinoma(FIGO I-II)is associated with a favorable outcome due to avoiding induction of premature surgical menopase without increasing risks of ovarian metastases or increasing cervical cancer related death-risks.
Keywords
Cervical cancer; ovarian preservation; staging
Statistics
Article View: 310
PDF Download: 122