IMMUNOLOGICAL STUDY ON CHICKENS VACCINATED WITH A COMBINED INACTIVATED SALMONELLA ENTERITIDIS AND NEWCASTLE DISEASE VIRUS (ND) VACCINE | ||||
Kafrelsheikh Veterinary Medical Journal | ||||
Article 4, Volume 9, Issue 2, October 2011, Page 59-72 PDF (484.49 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/kvmj.2011.113539 | ||||
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Authors | ||||
Anhar, M. Abd-ElMoaty* 1; Hanan, A. Ahmed1; Nahed, I. Mohamed1; Mervat, A. El-Koffy2 | ||||
1Central Laboratory for Quality Control of Veterinary Biologics | ||||
2Veterinary Serum and Vaccine Research Institute Abassia, Cairo Egypt, P.o.B.131 | ||||
Abstract | ||||
Immunogenicity of a locally prepared combined inactivated oil emulsified Salmonella enteritidis and Newcastle disease virus(SE-ND) vaccine was evaluated in 3-weeks old chickens. The immune response against single Salmonella enteritidis, Newcastle disease and combined (SE-ND) vaccines as measured by ELISA and heamagglutination inhibition (HI) test revealed no substantial differences with respect to the protective values between single and combined vaccine.The results of challenge test showed that vaccinated chickens were effectively protected against virulent strains of Salmonella enteritidis and Newcastle disease virus. The obtained results confirmed that the locally prepared combined inactivated Salmonella enteritidis and Newcastle disease virus was safe, potent and can effectively protect chickens against Salmonella enteritidis and Newcastle disease virus infection. | ||||
Keywords | ||||
chickens; Newcastle disease virus; Salmonella enteritidis; Immunogenicity | ||||
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