In vivo Evaluation of Antimicrobial Effect of Methanolic Extract of Chlorella vulgaris on Impetigo and Some Dermatophytes | ||||
| Egyptian Journal of Botany | ||||
| Article 5, Volume 56, Issue 2, February 2016, Page 423-437 PDF (528.97 K) | ||||
| DOI: 10.21608/ejbo.2016.1136 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| M. M. El-Sheekh* ; Shimaa M. El-Shafay; Enas M. El-Ballat | ||||
| Botany Department, Faculty of Science, Tanta University, | ||||
| Abstract | ||||
| IMPETIGO is one of the infectious superficial bacterial diseases and its treatment with antimicrobial agents may cause serious problems. So, a test of new microbial infection-fighting natural compounds is necessary. In the present study, histological examinations of the experimental animals revealed the effectiveness and safety of<i> Chlorella vulgaris </i>methanolic extract ointment used in the treatment of impetigo, tinea corporis and cutaneous candidiasis without any side effects on skin tissues. In addition, examination of skin sections treated with C.<i> Chlorella vulgaris</i> extract possessed no significant toxic effects. The skin appeared with normal epidermis as the keratinized fibers of stratum corneum were regularly arranged, appeared condensed without any disruption. The dermis appeared normal with minimal inflammatory cellular to infiltrate with the formation of hair follicles and sweat glands in comparison with a healthy skin. According to the chemical analyses of<i> Chlorella vulgaris</i>, the antimicrobial material was defined as a phenolic compound having the following formula C14H17NO4 and the suggested structure could be 2- (1- hydroxy-2- (4-hydroxyphenyl)-2- methoxyethyl - 4- oxopentane nitrile. | ||||
| Keywords | ||||
| <i> Chlorella vulgaris</i>; Antifungal; Antibacterial; Impetigo; Dermatophytes | ||||
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