EFFECT OF THE β-PYRMIMIDINE GLYCOSIDE VICINE EXTRACTED FROM FABA BEAN ON THE BIO-ANTIOXIDANT DEFENSE SYSTEM IN MALE REBBITS | ||||
| Kafrelsheikh Veterinary Medical Journal | ||||
| Article 3, Volume 4, Issue 2, October 2006, Page 35-44 PDF (585.64 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/kvmj.2006.114178 | ||||
 View on SCiNiTO | ||||
| Author | ||||
| Nasr A. Ziada* | ||||
| Nut. Deficiency Disease Unit. Animal Health Dept., Desert Res. Cenre, Cairo, Egypt. | ||||
| Abstract | ||||
| This study was done to investigate the peroxidative effects of the β- pyrimidine glycoside compound (vicine) extracted from the faba been by studying the chemical alterations of malondialdehyde (MDA) as a maker of free radical generation. This necessitate the evaluation of superoxide dismutase (SOD) in whole blood as these parameters are part of the antioxidant defense system. 48 rabbits were classified as three treated subgroup: 7, 14, 21 days vicine treated groups and 7, 14, 21 days saline injected control groups for comparison. The result showed that vicine from faba bean is a toxic substance and the effect was dose -time dependent. It enhance the free radical generation and alter TG and the activities of both GPx and SOD. It was concuded that the reactive pyrimidine glycoside (vicine) of faba bean is a toxic substance and considered as free radical generator. | ||||
| Keywords | ||||
| peroxidative effects; β- pyrimidine glycoside compound; rabbits | ||||
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