Early Epinephrine Administration in Patients with Cardiac Arrest in Case of Shockable Rhythm in ER
Alzahrani, K., Alghamdi, A., Alghamdi, O., Alrehaili, Y., Halawani, M., Almatrafi, S., Almotairi, A., AlMulhim, B., Alomar, N., Alkishi, A., Alreshidi, A., Alrajhi, B. (2018). Early Epinephrine Administration in Patients with Cardiac Arrest in Case of Shockable Rhythm in ER. EKB Journal Management System, 70(3), 439-445. doi: 10.12816/0043484
Khalid Yahya Alzahrani; Abdulaziz Saud Alghamdi; Omar Hussain Alghamdi; Yasser Musallam Alrehaili; Mahmoud Shehab Halawani; Saleh Jameel Almatrafi; Abdulkareem Khaled Almotairi; Bayan Jamal AlMulhim; Naif Khaled Alomar; Aman Abdullah Alkishi; Abeer Abdullah Alreshidi; Basil Mohammed Alrajhi. "Early Epinephrine Administration in Patients with Cardiac Arrest in Case of Shockable Rhythm in ER". EKB Journal Management System, 70, 3, 2018, 439-445. doi: 10.12816/0043484
Alzahrani, K., Alghamdi, A., Alghamdi, O., Alrehaili, Y., Halawani, M., Almatrafi, S., Almotairi, A., AlMulhim, B., Alomar, N., Alkishi, A., Alreshidi, A., Alrajhi, B. (2018). 'Early Epinephrine Administration in Patients with Cardiac Arrest in Case of Shockable Rhythm in ER', EKB Journal Management System, 70(3), pp. 439-445. doi: 10.12816/0043484
Alzahrani, K., Alghamdi, A., Alghamdi, O., Alrehaili, Y., Halawani, M., Almatrafi, S., Almotairi, A., AlMulhim, B., Alomar, N., Alkishi, A., Alreshidi, A., Alrajhi, B. Early Epinephrine Administration in Patients with Cardiac Arrest in Case of Shockable Rhythm in ER. EKB Journal Management System, 2018; 70(3): 439-445. doi: 10.12816/0043484

Early Epinephrine Administration in Patients with Cardiac Arrest in Case of Shockable Rhythm in ER

The Egyptian Journal of Hospital Medicine
Article 15, Volume 70, Issue 3, January 2018, Page 439-445  XML PDF (308.38 K)
Document Type: Original Article
DOI: 10.12816/0043484
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Authors
Khalid Yahya Alzahrani1; Abdulaziz Saud Alghamdi1; Omar Hussain Alghamdi1; Yasser Musallam Alrehaili2; Mahmoud Shehab Halawani3; Saleh Jameel Almatrafi4; Abdulkareem Khaled Almotairi4; Bayan Jamal AlMulhim5; Naif Khaled Alomar6; Aman Abdullah Alkishi7; Abeer Abdullah Alreshidi8; Basil Mohammed Alrajhi9
1King Abdulaziz University
2King Fahad Hospital
3Ohud Hospital
4Ibn Sina National College
5King Faisal University
6Imam Mohammed Bin Saud Islamic University
7Alfaisal University
8International Academy for Health Science
9Albatterjee Medical College, SA
Abstract
    The objective of the review was to investigate the scientific production and evaluate the effectiveness of epinephrine in the treatment of cardiac arrest in terms of survival and neurological status. PubMed, Embase, and Google Scholar databases were searched up till November 2017 for published studies in English language and human subjects discussing early epinephrine administration in patients with cardiac arrest in case of shockable rhythm in emergency medicine. Prehospital epinephrine management may increase short-term survival (ROSC) yet does not improve survival to release, or neurologic results after out-of-hospital cardiac arrest OHCA. Although there is no clear proof of long-lasting advantages complying with the use of epinephrine in OHCA, there is insufficient evidence to sustain altering present guidelines which recommend its management (1 mg every 3-5 min) throughout resuscitation. As a result, there is a need for additional clinical trials to analyze whether lower dosages or alternative regimes of epinephrine administration. Furthermore, one of the most important aspects of care in cardiac arrest is basic life support (BLS) measures, consisting of adequate compressions and early defibrillation.
Keywords
Epinephrine; Cardiac Arrest; Shockable Rhythm
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