Narrative Review on Different Clinical Aspects of Thrombocytopenia
Alghamdi, A., Alzahrani, K., Alghamdi, O., Altaleb, A., Mauqary, M., Alrufayyiq, S., Alanizy, F., Halawani, O., Alhasnani, M., Alrehaili, Y., Aldor, A. (2018). Narrative Review on Different Clinical Aspects of Thrombocytopenia. EKB Journal Management System, 70(3), 446-451. doi: 10.12816/0043485
Abdulaziz Saud Alghamdi; Khalid Yahya Alzahrani; Omar Hussain Alghamdi; Abdulraouf Muhammad Altaleb; Majed Abdulaziz Mauqary; Saleh Ibrahim Alrufayyiq; Faisal Fahad Alanizy; Olfa Ahmed Halawani; mohammad Hamdin Alhasnani; Yasser Musallam Alrehaili; abdullah Mahmoud Aldor. "Narrative Review on Different Clinical Aspects of Thrombocytopenia". EKB Journal Management System, 70, 3, 2018, 446-451. doi: 10.12816/0043485
Alghamdi, A., Alzahrani, K., Alghamdi, O., Altaleb, A., Mauqary, M., Alrufayyiq, S., Alanizy, F., Halawani, O., Alhasnani, M., Alrehaili, Y., Aldor, A. (2018). 'Narrative Review on Different Clinical Aspects of Thrombocytopenia', EKB Journal Management System, 70(3), pp. 446-451. doi: 10.12816/0043485
Alghamdi, A., Alzahrani, K., Alghamdi, O., Altaleb, A., Mauqary, M., Alrufayyiq, S., Alanizy, F., Halawani, O., Alhasnani, M., Alrehaili, Y., Aldor, A. Narrative Review on Different Clinical Aspects of Thrombocytopenia. EKB Journal Management System, 2018; 70(3): 446-451. doi: 10.12816/0043485

Narrative Review on Different Clinical Aspects of Thrombocytopenia

The Egyptian Journal of Hospital Medicine
Article 16, Volume 70, Issue 3, January 2018, Page 446-451  XML PDF (304.34 K)
Document Type: Original Article
DOI: 10.12816/0043485
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Authors
Abdulaziz Saud Alghamdi1; Khalid Yahya Alzahrani1; Omar Hussain Alghamdi1; Abdulraouf Muhammad Altaleb1; Majed Abdulaziz Mauqary1; Saleh Ibrahim Alrufayyiq2; Faisal Fahad Alanizy2; Olfa Ahmed Halawani3; mohammad Hamdin Alhasnani4; Yasser Musallam Alrehaili5; abdullah Mahmoud Aldor6
1king Abdulaziz University
2king Saud Bin Abdulaziz University For Health Sciences
3Ibn Sina National College
4Umm Al-Qura University
5King Fahad Hospital
6October 6 University
Abstract
     This review article aims to summarize the major causes of thrombocytopenia and characterize the main general symptoms of thrombocytopenia. As well we summarize the diagnosis and treatment methods. We conducted the search using electronic biomedical databases such as; Medline, and Embase, for studies published up to September 2017 in the English language concerning the thrombocytopenia in general. Thrombocytopenia can either be primary or secondary, in that it could go along with a broad spectrum of syndromes and diseases and may be triggered by different systems. Trigger investigation and recognition might be important and sometimes life-saving as in TTP, heparin-induced thrombocytopenia, acute leukemia or perhaps severe ITP. Taking a detailed history and a thorough physical examination can give clues concerning possible underlying illness and clinical treatments. Cautious evaluation of the peripheral blood smear is necessary. When the differential diagnosis is problematic, sometimes a short trial of therapy could help to clarify the reason. For instance, it might be difficult to differentiate inherited thrombocytopenia (without a family history) from immune thrombocytopenia (ITP); in this example, intravenous immunoglobulin infusion will likely have no effect in inherited thrombocytopenia, however, will generally be useful in ITP.
Keywords
Clinical Aspects; thrombocytopenia; intravenous immunoglobulin infusion
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