CLINICOPATHOLOGICAL STUDIES ON THE EFFECT OF PEFLOXACIN ADMINISTRATION ON E. COLI INFECTED CHICKS | ||||
| Kafrelsheikh Veterinary Medical Journal | ||||
| Article 10, Volume 5, Issue 1, April 2007, Page 166-179 PDF (627.15 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/kvmj.2007.115876 | ||||
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| Author | ||||
| A.G. Selim* | ||||
| The Veterinary Clinic Fac. of Vet. Med., Zagazig University. | ||||
| Abstract | ||||
| This study was planed to investigate the effect of Pefloxacin on hematological and biochemical alterations in broiler chicks experimentally infected with E. coli. One hundred and twenty apparently healthy unsexed, one day old native broiler chicks were divided into 4 equal groups, each 30 chicks. Group (A) was kept as control group (non infected non treated). Group (B) was infected by E. coli. Group (C) infected and treated with Pefloxacin 50mg/L for three successive days. Group (D) treated only with Pefloxacin 50mg/L for three successive days. Erythrogram data for E. coli infected groups reveled macrocytic hypochromic anemia, while infected group showed marked leukocytosis, heterophilia and monocytosis allover the experimental period. The pefloxacin treatment group showed heterophilia and monocytosis only. The activities of AST, ALT and ALP were significantly elevated with E. coli infection and Pefloxacin treated group at 14 days old. Hypoproteinemia, hypoalbunemia and hypoglobuliemia observed in infected groups. Elevated serum uric acid and creatinine have been reported in both infected groups. | ||||
| Keywords | ||||
| Pefloxacin; hematological and biochemical alterations; broiler chicks; E. coli | ||||
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