SYNTHESIS OF SOME NOVEL PYRIDINE, THIOPHENE, THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES CONTAINING BENZOFURANYL MOIETY | ||||
| Al-Azhar Bulletin of Science | ||||
| Article 5, Volume 17, Issue 1-A, June 2006, Page 65-75 PDF (370.32 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/absb.2006.11640 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| J. A. MICKY* ; N. M. SALEH; N. M. SHEMISS; S. A. MOHAMED | ||||
| Chemistry Department, Faculty of Science (Girl’s), Al-Azhar University–Nasr City, Cairo, Egypt. | ||||
| Abstract | ||||
| Interaction of 2-[1-(4,6-dimethoxybenzofuran-5-yl)ethylidine]malononitrile (1) with phenylisocyanate, phenylhydrazine, carbon disulphide and arylidenemalono-nitrile afforded the corresponding pyridine 2, pyrido[2,3-d] pyrimidine 3, phenylhydrazone 4,pyridine 2,6-dithione 8 and benzene dicarbonitrile 9 derivatives . Treatment of 1 with elemental sulfur under Gewald reaction conditions furnished 2-amino-4-(4,6-dimethoxybenzofuran-5-yl)thiophen-3-carbonitrile 11 which used as starting material in the synthesis of thienopyrimidine 14 and thienopyridine 15 derivatives. | ||||
| Keywords | ||||
| Pyridine; THIOPHENE; THIENOPYRIMIDINE; THIENOPYRIDINE; BENZOFURANYL | ||||
|
Statistics Article View: 172 PDF Download: 258 |
||||
