Audio-Vestibular Findings in Patients with Hyperuricemia | ||||
| International Journal of Medical Arts | ||||
| Article 27, Volume 2, Issue 4, October 2020, Page 866-872 PDF (2.11 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ijma.2020.38516.1153 | ||||
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| Authors | ||||
Mohamed Mahmoud Al-Sobki  1; Gehan Abd-Al-Rahman El-Zarea2; Ahmed Mohamed Ahmed Mahmoud2; Ahmed Abd El Moez Ali Saad3
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| 1Audiovestibular Unit, Department of Otorhinolaryngology, Damietta Faculty of Medicine, Al-Azhar University, Egypt | ||||
| 2Audiovestibular Unit, Depart of Otorhinolaryngology, Faculty of Medicine, Al-Azhar University, Egypt | ||||
| 3Department of Clinical pathology, Faculty of Medicine-Al-Azhar University, Egypt | ||||
| Abstract | ||||
| Background: Hyperuricemiais a common biochemical disturbance in which serum concentration of uric acid exceeds the normal values which is 7.0 mg/dl in men and more than 6.0 mg/dl in women leading to deposition of monosodium urate [MSU] crystals in joints and soft tissues resulting in inner ear functions affection. Aim of the work: To elaborate the effect of hyperuricemia on the peripheral hearing as well as peripheral vestibular functions. Subjects and Methods: This study included 40 subjects with hyperuricemia and 40 healthy controls. Participants underwent serum uric acid assay, full history taking, basic audiological evaluation and vestibular evaluation. Results: 37[92.5%] hyperuricemic subjects had normal peripheral hearing sensitivity, only 3[7.5%] had mild high frequencies sensori-neural hearing loss [SNHL] at 8 kHz. 31[77.5%] Hyperuricemic patients had normal peripheral vestibular functions, only 9[22.5%] subjects had BPPV; They also had higher serum uric acid [SUA] level. No correlation between duration of hyperuricemia and occurrence of BPPV. Conclusions: The hyperuricemic subjects had a significant higher incidence of BPPV. Other investigations to detect early and subtle changes in cochlear function of hyperuricemic subjects were recommended. | ||||
| Keywords | ||||
| Audio-vestibular; Sensorineural hearing loss; Vertigo; Hyperuricemia, Uric Acid | ||||
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