Correlative Study Of Serum Level Of 25-hydroxy Vitamin D With Functional Disability And Neuropathic Pain In Rheumatoid Arthritis Patients
Elfetiany, D., Mohasseb, D., Farahat, N., Abd Elnaby, H. (2020). Correlative Study Of Serum Level Of 25-hydroxy Vitamin D With Functional Disability And Neuropathic Pain In Rheumatoid Arthritis Patients. EKB Journal Management System, 2(2), 28-28. doi: 10.21608/alexpo.2020.44743.1045
Doaa Elfetiany; Diaa Fahmy Mohasseb; Nahla Mohamed Farahat; Hoda Mohamed Abd Elnaby. "Correlative Study Of Serum Level Of 25-hydroxy Vitamin D With Functional Disability And Neuropathic Pain In Rheumatoid Arthritis Patients". EKB Journal Management System, 2, 2, 2020, 28-28. doi: 10.21608/alexpo.2020.44743.1045
Elfetiany, D., Mohasseb, D., Farahat, N., Abd Elnaby, H. (2020). 'Correlative Study Of Serum Level Of 25-hydroxy Vitamin D With Functional Disability And Neuropathic Pain In Rheumatoid Arthritis Patients', EKB Journal Management System, 2(2), pp. 28-28. doi: 10.21608/alexpo.2020.44743.1045
Elfetiany, D., Mohasseb, D., Farahat, N., Abd Elnaby, H. Correlative Study Of Serum Level Of 25-hydroxy Vitamin D With Functional Disability And Neuropathic Pain In Rheumatoid Arthritis Patients. EKB Journal Management System, 2020; 2(2): 28-28. doi: 10.21608/alexpo.2020.44743.1045

Correlative Study Of Serum Level Of 25-hydroxy Vitamin D With Functional Disability And Neuropathic Pain In Rheumatoid Arthritis Patients

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Article 2, Volume 2, Issue 2, October 2020, Page 28-28  XML
Document Type: Preliminary preprint short reports of original research
DOI: 10.21608/alexpo.2020.44743.1045
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Authors
Doaa Elfetiany email 1; Diaa Fahmy Mohasseb1; Nahla Mohamed Farahat2; Hoda Mohamed Abd Elnaby3
1Physical medicine, Rheumatology and Rehabilitation, Faculty of medicine, Alexandria University, Alexandria, Egypt
2Clinical and chemical Pathology, Faculty of Medicine, University of Alexandria, Alexandria, Egypt.
3Physical Medicine, Rheumatology and Rehabilitation, Faculty of Medicine, University of Alexandria, Alexandria, Egypt.
Abstract
Rheumatoid arthritis is a chronic systemic autoimmune inflammatory disease that affect all ethnic groups more in females. It is the result of genetic and environmental factors interaction. The pathogenesis includes interconnected cellular molecular pathways leading to destruction of cartilage and bone.
Vitamin D is a steroid hormone, in addition to its main effects on bone and calcium metabolism, it has other functions in the body, including cell growth regulation, reduction of inflammation and immune and neuromuscular function. functions, plays an important role in calcium homeostasis and bone health.
Evidence has accumulated regarding immune-modulatory actions of vitamin D, and its significant role in different processes of the immune system, namely, stimulating the innate immune system and inhibiting the adaptive immune responses
The immuno-modulatory activities of Vitamin D might be particularly efficient in RA patients and support a therapeutic role of Vitamin D in these patients.
The relationship between the severity of RA and levels of Vitamin D is a subject of immense
interest and therapeutic implications.
The aim of this work is to study the correlation of serum level of 25-hydroxy vitamin D with functional disability and neuropathic pain in rheumatoid arthritis patients.
Keywords
Rheumatoid arthritis; Vitamin D; Neuropathic pain
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