Solid Phase Synthesis of I25 Labeled Insulin Fragments. Part III. Synthesis of 125-I-Insulin Fragment B15-18 Leu-Tyr(I2)-Leu-Val | ||||
Egyptian Journal of Chemistry | ||||
Article 5, Volume 55, Issue 6, December 2012, Page 639-647 PDF (443.61 K) | ||||
DOI: 10.21608/ejchem.2012.1178 | ||||
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Abstract | ||||
NOWA DAYS, synthesis of biological active peptides has been found in an impressive success. This has been achieved by development of new techniques, using new reagents and easy reach. A new approach to radio-peptides synthesis has been investigated in an effort to overcome the technical difficulties of separation, purification and identification of the prepared peptide fragments. In a series of solid-phase peptide synthesis of labeled insulin fragments, we have prepared 125-I-Insulin fragment Bl 5-18. In this research work we discussed the synthesis of Insulin fragment B15-18 Labeled with Leu-Tyr(I 2 )-Leu-Val. | ||||
Keywords | ||||
Amino acids; Insulin; iodine 125; Labeling; Peptide hormones and Synthesis | ||||
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