Clinical and Radiographic Evaluation of Ten Congenital Insensitivity to Pain with Anhidrosis Patients | ||||
Al-Azhar Dental Journal for Girls | ||||
Article 1, Volume 7, 4-B, October 2020, Page 557-583 PDF (369.84 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/adjg.2020.13139.1150 | ||||
View on SCiNiTO | ||||
Authors | ||||
Heba M. Gamal El Din 1; Naglaa S. El kilani2; Mostafa I. Mostafa3; Inas Sayed4; Samira Ismail5; Eatemad Shoreibah6 | ||||
1Assistant Researcher of Oro-dental Genetics, Department of Oro-dental Genetics, Human genetics and genome research division, National Research Center, Cairo, Egypt | ||||
2Professor and Head of Oral medicine, Periodontology, Diagnosis and Radiology Department, Faculty of Dental medicine for Girls, Al Azhar university, Cairo, Egypt | ||||
3Professor of Oro-dental Genetics, Department of Oro-dental Genetics, Human genetics and genome research division, National Research Center, Cairo, Egypt | ||||
4Researcher of Oro-dental Genetics, Department of Oro-dental Genetics, Human genetics and genome research division, National Research Center, Cairo, Egypt | ||||
5Professor of Clinical Genetics, Clinical Genetics Department, Human Genetics and Genome Research Division, National Research Center, Cairo, Egypt | ||||
6Professor of Oral medicine, Periodontology, Diagnosis and Radiology Department, Faculty of Dental medicine for Girls, Al Azhar university, Cairo, Egypt | ||||
Abstract | ||||
Purpose: This study was designed to introduce a standardized protocol for examination of congenital insensitivity to pain with anhidrosis patients. And also report the oro-dental manifestations in these patients. Materials and methods: In the current study, Oro-facial clinical and sensory examinations, as well as radiographic examination for ten CIPA patients were performed. Results: The Oro-dental findings were mainly missing teeth and soft tissue injuries. Radiographic examination revealed multiple congenitally missing teeth. Conclusion: A standardized protocol with Oro-facial clinical and sensory examinations, pulp sensitivity tests and radiographic examination should be considered as a primary diagnostic approach in patients with suspected Congenital insensitivity to pain with anhidrosis, instead of the more established but expensive molecular analysis and the invasive Sural nerve biopsy. | ||||
Keywords | ||||
Anhidrosis; Self-mutilation; oro-facial injuries; premature tooth loss | ||||
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