Fluoride alternatives for remineralization of early enamel carious lesions, Fact or Fiction?- A Systematic Review
Attia, N., Hasan, M., Sallam, N. (2020). Fluoride alternatives for remineralization of early enamel carious lesions, Fact or Fiction?- A Systematic Review. EKB Journal Management System, 66(Issue 4 - October (Orthodontics, Pediatric & Preventive Dentistry)), 1971-1979. doi: 10.21608/edj.2020.36600.1179
Nasr Mohamed Attia; Mahmoud Mohammed Hasan; Nadhem Mohammed Sallam. "Fluoride alternatives for remineralization of early enamel carious lesions, Fact or Fiction?- A Systematic Review". EKB Journal Management System, 66, Issue 4 - October (Orthodontics, Pediatric & Preventive Dentistry), 2020, 1971-1979. doi: 10.21608/edj.2020.36600.1179
Attia, N., Hasan, M., Sallam, N. (2020). 'Fluoride alternatives for remineralization of early enamel carious lesions, Fact or Fiction?- A Systematic Review', EKB Journal Management System, 66(Issue 4 - October (Orthodontics, Pediatric & Preventive Dentistry)), pp. 1971-1979. doi: 10.21608/edj.2020.36600.1179
Attia, N., Hasan, M., Sallam, N. Fluoride alternatives for remineralization of early enamel carious lesions, Fact or Fiction?- A Systematic Review. EKB Journal Management System, 2020; 66(Issue 4 - October (Orthodontics, Pediatric & Preventive Dentistry)): 1971-1979. doi: 10.21608/edj.2020.36600.1179

Fluoride alternatives for remineralization of early enamel carious lesions, Fact or Fiction?- A Systematic Review

Egyptian Dental Journal
Article 7, Volume 66, Issue 4 - October (Orthodontics, Pediatric & Preventive Dentistry), October 2020, Page 1971-1979  XML PDF (589.15 K)
Document Type: Original Article
DOI: 10.21608/edj.2020.36600.1179
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Authors
Nasr Mohamed Attiaorcid 1; Mahmoud Mohammed Hasan email 2; Nadhem Mohammed Sallam3
1Department of Pedodontic, Dental Public Health and Preventive Dentistry. Faculty of Dentistry, Mansoura University. Egypt
2Pediatric and Preventive Dentistry Department, Mansoura University, Mansoura, Egypt
3Ph.D. in Pediatric Dentistry, Pediatric and Preventive Dentistry Department. Faculty of Dentistry, Mansoura University. Egypt.
Abstract
Aim: The purpose of this study was to systematically assess the quality of evidence supporting fluoride's alternatives for treating early enamel caries. Methods: A broad search strategy using PubMed and other sources was performed. For sensitive search strategy, we used MESH database and the following search queries: (‘‘Remineralization’’ [Mesh] OR ‘‘Remineralisation’’) AND (‘‘Caries’’ [Mesh] OR ‘‘Decay’’) AND (‘‘Fluoride’’). Predetermined criteria were: parallel, randomized, controlled trial studies with 6 to 18 years old children. Results: 1919 articles from PubMed advanced search were initially revealed then 79 papers were picked up, in addition to 536 from other sources. One paper only removed as a duplicate (by the author, title and reference). The remaining articles were indicated for closer assessment. Out of 614 papers were screened by title, only 29 met the inclusion criteria of this review. Additional screening by abstract was done independently by the three researchers to result in 7 articles. Conclusion: From this review, there is moderate clinical evidence to support preventive agents as fluoride substitutes. This review suggests the use of resin infiltration and fluoridated Miswak as remineralizing agents.
Keywords
Early enamel caries; Fluoride; Remineralizing agents
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