PHYTOCHEMICAL AND BIOLOGICAL STUDIES ON SOME MEDICINAL PLANTS | ||||
| Al-Azhar Journal of Pharmaceutical Sciences | ||||
| Article 8, Volume 62, Issue 2, September and October 2020, Page 110-134 PDF (1.48 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ajps.2020.118379 | ||||
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| Author | ||||
| Amina El-Kelany | ||||
| Department of Botany and Microbiology, Faculty of Science, Al-Azhar, University, Girl Branch, Cairo, Egypt. | ||||
| Abstract | ||||
| Biological studies on thirteen ethanolic plant extracts (Rosmarinus officinalis ,Ocimum basilicum , Moringa oleifera, Zingiber officinale, Curcuma longa, Nigella sativa ,Cinnamomum verum ,Salvia officinalis, Lepidium sativum, Foeniculum vulgare, Anethum graveolens, Ficus benghalensis and Cinnamomum camphora )revealed that four of them (Rosmarinus officinalis , Zingiber officinale, Cinnamomum verum and Cinnamomum camphora) were the best active against two bacterial species ; E. coli , S .aureus and one fungus species C. albicans. Also, their synergistic effects against E. coli, S. aureus and C. albicans were studied .So, the phytochemical studies were completed on these four plants . This study aimed to evaluate the chemical composition of the best active plant extracts. The chemical major content of Rosmarinus officinalis was eucalyptol (7.48%) , Zingiber officinale was gingerol (12.73%) , Cinnamomum verum was (E)- cinnamaldehyde (25.55 % ) and Cinnamomum camphora was eugenol ( 27 .35% ) . The minimum inhibitory concentration (MIC) values varied from 0.625 to 2.5 mg/ml, for the S. aureus (gram positive bacteria) affected by Rosmarinus officinali, Zingiber officinale, Cinnamomum verum and Cinnamomum camphora. Respectively. C. albicans was the most effective microorganism by Cinnamomum verum and the least effective microorganism by Rosmarinus officinalis and Cinnamomum camphora. ethanolic extracts, as MIC ranged from 0.15 to 1.25 mg/ml. | ||||
| Keywords | ||||
| Escherichia coli; Staphylococcus aureus; Candida albicans; Rosmarinus officinalis; Zingiber officinale; Cinnamomum verum; Cinnamomum camphora; antimicrobial activity; Minimum inhibitory concentration (MIC) | ||||
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