MRI Enhancement as A Predicator of Uterine Fibroid Volume Reduction after Embolism | ||||
The Egyptian Journal of Hospital Medicine | ||||
Article 13, Volume 69, Issue 4, October 2017, Page 2254-2257 PDF (282.92 K) | ||||
Document Type: Original Article | ||||
DOI: 10.12816/0041526 | ||||
View on SCiNiTO | ||||
Authors | ||||
Amor Abdullah Al Mehdar1; Alaa Ibrahim Tukruna2; Abdulaziz Raja Najim Alotaibi3; Alaa Mohammed Ali Alshahrani4; Fatimah Nasser Alsaad5; Zahra Adel Ali Jaffa6; Azharmuslimsarhan Aljohan7; Zahra Ibrahim Alqarrash5; Hajarayad Alluhaybi7; Afnan Omer Aludaini8; Luayesam Hakami9; Amnah Abdullah Alanzi10; Abdullah Abdulrahman I Muharib11; Abdulsalam Ibrahim A. Althumairy4; Atheer Raja Alyami12 | ||||
1Ministry of Health | ||||
2Batterjee Medical College | ||||
3King Faisal Medical Complex | ||||
4King Khalid University | ||||
5Imam Abdulrahman Bin Faisal University | ||||
6Almaarefa Colleges | ||||
7Taibah University | ||||
8King Abdulaziz University | ||||
9Umm Al-Qura University | ||||
10University of Tabuk | ||||
11King Saud Bin Abdulaziz University for Health Sciences | ||||
12Najran University | ||||
Abstract | ||||
Aim of the Study: To evaluate the response of necrotic fibroids to UAE and to identify whether pre-UAE enhancement or other factors are predictors of fibroid shrinkage. Materials and methods: This is a retrospective review of all women who underwent UAE for symptomatic fibroids from January 2013 till July 2017, who experienced a follow-up MRI 5-6 months after UAE were included. There were 54 fibroids (37 non-enhancing and 17 enhancing) among 24 women with a mean age of 56 (range 40-59) years. All fibroids were assessed for size, position, enhancement on subtraction images, and Apparent Diffusion Constant (ADC). Results: Enhancing fibroids had an average decrease in diameter by 23 ± 6%, not significantly different compared to that non-enhancing fibroids which decreased by 19 ± 3% (p=0.491). Multiple linear regression with percent change in fibroid diameter as the dependent variable and patient age, fibroid position, and pre-UAE fibroid diameter, enhancement, and ADC as independent variables, showed that ADC (p<0.005) and pre-UAE diameter (p<0.005) were the only significant independent variables. Conclusion: Pre-UAE size and ADC, but not contrast enhancement, predicted fibroid diameter reduction. Enhancing and non-enhancing fibroids had similar size reduction after UAE. Non-enhancement should not be considered a contraindication to UAE. | ||||
Keywords | ||||
MRI; diffusivity; Uterine artery embolization; Fibroid | ||||
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