MRI Enhancement as A Predicator of Uterine Fibroid Volume Reduction after Embolism
Al Mehdar, A., Tukruna, A., Alotaibi, A., Alshahrani, A., Alsaad, F., Jaffa, Z., Aljohan, A., Alqarrash, Z., Alluhaybi, H., Aludaini, A., Hakami, L., Alanzi, A., Muharib, A., Althumairy, A., Alyami, A. (2017). MRI Enhancement as A Predicator of Uterine Fibroid Volume Reduction after Embolism. EKB Journal Management System, 69(4), 2254-2257. doi: 10.12816/0041526
Amor Abdullah Al Mehdar; Alaa Ibrahim Tukruna; Abdulaziz Raja Najim Alotaibi; Alaa Mohammed Ali Alshahrani; Fatimah Nasser Alsaad; Zahra Adel Ali Jaffa; Azharmuslimsarhan Aljohan; Zahra Ibrahim Alqarrash; Hajarayad Alluhaybi; Afnan Omer Aludaini; Luayesam Hakami; Amnah Abdullah Alanzi; Abdullah Abdulrahman I Muharib; Abdulsalam Ibrahim A. Althumairy; Atheer Raja Alyami. "MRI Enhancement as A Predicator of Uterine Fibroid Volume Reduction after Embolism". EKB Journal Management System, 69, 4, 2017, 2254-2257. doi: 10.12816/0041526
Al Mehdar, A., Tukruna, A., Alotaibi, A., Alshahrani, A., Alsaad, F., Jaffa, Z., Aljohan, A., Alqarrash, Z., Alluhaybi, H., Aludaini, A., Hakami, L., Alanzi, A., Muharib, A., Althumairy, A., Alyami, A. (2017). 'MRI Enhancement as A Predicator of Uterine Fibroid Volume Reduction after Embolism', EKB Journal Management System, 69(4), pp. 2254-2257. doi: 10.12816/0041526
Al Mehdar, A., Tukruna, A., Alotaibi, A., Alshahrani, A., Alsaad, F., Jaffa, Z., Aljohan, A., Alqarrash, Z., Alluhaybi, H., Aludaini, A., Hakami, L., Alanzi, A., Muharib, A., Althumairy, A., Alyami, A. MRI Enhancement as A Predicator of Uterine Fibroid Volume Reduction after Embolism. EKB Journal Management System, 2017; 69(4): 2254-2257. doi: 10.12816/0041526

MRI Enhancement as A Predicator of Uterine Fibroid Volume Reduction after Embolism

The Egyptian Journal of Hospital Medicine
Article 13, Volume 69, Issue 4, October 2017, Page 2254-2257  XML PDF (282.92 K)
Document Type: Original Article
DOI: 10.12816/0041526
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Authors
Amor Abdullah Al Mehdar1; Alaa Ibrahim Tukruna2; Abdulaziz Raja Najim Alotaibi3; Alaa Mohammed Ali Alshahrani4; Fatimah Nasser Alsaad5; Zahra Adel Ali Jaffa6; Azharmuslimsarhan Aljohan7; Zahra Ibrahim Alqarrash5; Hajarayad Alluhaybi7; Afnan Omer Aludaini8; Luayesam Hakami9; Amnah Abdullah Alanzi10; Abdullah Abdulrahman I Muharib11; Abdulsalam Ibrahim A. Althumairy4; Atheer Raja Alyami12
1Ministry of Health
2Batterjee Medical College
3King Faisal Medical Complex
4King Khalid University
5Imam Abdulrahman Bin Faisal University
6Almaarefa Colleges
7Taibah University
8King Abdulaziz University
9Umm Al-Qura University
10University of Tabuk
11King Saud Bin Abdulaziz University for Health Sciences
12Najran University
Abstract
Aim of the Study:  To evaluate the response of necrotic fibroids to UAE and to identify whether pre-UAE enhancement or other factors are predictors of fibroid shrinkage.
Materials and methods: This is a retrospective review of all women who underwent UAE for symptomatic fibroids from January 2013 till July 2017, who experienced a follow-up MRI 5-6 months after UAE were included. There were 54 fibroids (37 non-enhancing and 17 enhancing) among 24 women with a mean age of 56 (range 40-59) years. All fibroids were assessed for size, position, enhancement on subtraction images, and Apparent Diffusion Constant (ADC).
Results: Enhancing fibroids had an average decrease in diameter by 23 ± 6%, not significantly different compared to that non-enhancing fibroids which decreased by 19 ± 3% (p=0.491). Multiple linear regression with percent change in fibroid diameter as the dependent variable and patient age, fibroid position, and pre-UAE fibroid diameter, enhancement, and ADC as independent variables, showed that ADC (p<0.005) and pre-UAE diameter (p<0.005) were the only significant independent variables.
Conclusion:   Pre-UAE size and ADC, but not contrast enhancement, predicted fibroid diameter reduction. Enhancing and non-enhancing fibroids had similar size reduction after UAE. Non-enhancement should not be considered a contraindication to UAE.
 
Keywords
MRI; diffusivity; Uterine artery embolization; Fibroid
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