An aggressive central giant cell granuloma of maxilla: Diagnostic dilemma, Precise differential diagnosis and successful traditional surgical approach: A case report
Elmezwghi, A., Alarabi, N., Elsagali, A., Zariba, S., BenGharbia, N., Musa, N. (2020). An aggressive central giant cell granuloma of maxilla: Diagnostic dilemma, Precise differential diagnosis and successful traditional surgical approach: A case report. EKB Journal Management System, 66(Issue 4 - October (Oral Surgery)), 2075-2083. doi: 10.21608/edj.2020.40494.1226
Abdurahman Musbah Elmezwghi; Nuri Mustafa Alarabi; Abeer Hussein Elsagali; Salma S. Mo Zariba; Najia Emhemed BenGharbia; Nesrin Hassan Musa. "An aggressive central giant cell granuloma of maxilla: Diagnostic dilemma, Precise differential diagnosis and successful traditional surgical approach: A case report". EKB Journal Management System, 66, Issue 4 - October (Oral Surgery), 2020, 2075-2083. doi: 10.21608/edj.2020.40494.1226
Elmezwghi, A., Alarabi, N., Elsagali, A., Zariba, S., BenGharbia, N., Musa, N. (2020). 'An aggressive central giant cell granuloma of maxilla: Diagnostic dilemma, Precise differential diagnosis and successful traditional surgical approach: A case report', EKB Journal Management System, 66(Issue 4 - October (Oral Surgery)), pp. 2075-2083. doi: 10.21608/edj.2020.40494.1226
Elmezwghi, A., Alarabi, N., Elsagali, A., Zariba, S., BenGharbia, N., Musa, N. An aggressive central giant cell granuloma of maxilla: Diagnostic dilemma, Precise differential diagnosis and successful traditional surgical approach: A case report. EKB Journal Management System, 2020; 66(Issue 4 - October (Oral Surgery)): 2075-2083. doi: 10.21608/edj.2020.40494.1226

An aggressive central giant cell granuloma of maxilla: Diagnostic dilemma, Precise differential diagnosis and successful traditional surgical approach: A case report

Egyptian Dental Journal
Article 1, Volume 66, Issue 4 - October (Oral Surgery), October 2020, Page 2075-2083  XML PDF (2.16 MB)
Document Type: Original Article
DOI: 10.21608/edj.2020.40494.1226
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Authors
Abdurahman Musbah Elmezwghi1; Nuri Mustafa Alarabi2; Abeer Hussein Elsagali3; Salma S. Mo Zariba4; Najia Emhemed BenGharbia5; Nesrin Hassan Musa6
1Oral Pathology Dept. Faculty of Dentistry. University of Tripoli. Tripoli-Libya.
2Oral and Maxillofacial Dept. Faculty of Dentistry. University of Tripoli. Tripoli -Libya
3Oral and Maxillofacial Surgery Dept. Faculty of Dentistry. University of Tripoli. Tripoli-Libya
4Oral maxillofacial Surgery Dept. Faculty of Dentistry. University of Tripoli. Tripoli-Libya
5Oral and Maxillofacial Dept. Faculty of Dentistry. University of Tripoli. Tripoli-Libya.
6Oral and Maxillofacial Surgery Dept. Faculty of Dentistry. University of Tripoli. Tripoli-Libya.
Abstract
Abstract
Central Giant Cell Granuloma (CGCG) is a benign, proliferative, intraosseous and non-odontogenic lesion of unknown etiology accounting for approximately 10% of all benign lesions of the jawbones. Lesion usually occurs in patients younger than 30 years, is more common in females than males, and is more common in mandible than maxilla. The clinical feature of CGCG ranges from a slow growing asymptomatic swelling to a rapidly enlarging aggressive lesion. CGCG of the jaws are histologically benign lesions characterized by the presence of giant cells in the richly vascularized stroma of the spindle cells. Differential diagnosis should be performed with other lesions that have multinucleated giant cells (MGCs). Definitive diagnosis relies on correct interpretation of clinical, radiographical and histopathological data. The treatment of CGCG ranges from curettage to resection. Alternative treatments are worthy of consideration, although surgical excision remains the treatment of choice.
The aim of this presented case highlights a diagnostic challenge of an aggressive CGCG arising from the maxilla and to discuss a precise differential diagnosis, as well as the surgical approach and follow up which is decisive for successful conventional surgical treatment with no lesion recurrence.
Keywords
Keywords: Central giant cell granuloma; aggressive and non-aggressive form; differential diagnosis; traditional surgical treatment; Recurrence follows up
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