Synthesis and Microstructure Characterization of Novel Sr-HA Prepared by Co-precipitation with Enhanced Bioactivity | ||||
| Egyptian Journal of Biomedical Engineering and Biophysics | ||||
| Article 6, Volume 13, Issue 1, December 2012, Page 73-85 PDF (489.71 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejbbe.2012.1194 | ||||
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| Abstract | ||||
| THERE IS accumulating evidence that strontium-containing biomaterials have positive effects on bone tissue repair. In this study, a series of Sr-substituted hydroxyapatites (SrxCa1-x)5 (PO4)3OH, where x = 0.00, 0.5, 1.00 and 2.00 were made by the co-precipitation method. The microstructure analyses of obtained apatite after incorporation of Sr were evaluated by using X-ray Diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), Scanning electron microscope (SEM) and Thermo gravimetric analysis (TGA). Moreover, bioactivity of samples was examined by soaking samples in the simulated body fluid solution (SBF). Strontium is quantitatively incorporated into hydroxyapatite where its substitution for calcium provokes a linear increase in the lattice constants and a linear shift of the infrared absorption bands of the hydroxyl and phosphate groups, coherent with the greater ionic radius of strontium .Also incorporation of Sr into hydroxyapatite provokes its thermal stability and bioactivity. The obtained results indicate that Sr-HA have high potential to be used as a resorbable scaffold material release therapeutic agent to enhance osteogenesis and bone regeneration. | ||||
| Keywords | ||||
| Hydroxyapatite; Sr-substituted hydroxyapatite; Crystal size; Bioactivity; Simulated body fluid | ||||
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