Relation between serum levels of Vitamin D and Immunoglobulin E in Allergic Rhinitis in Upper Egypt
Abdelmaksoud, A., Bazeed, S., Alemam, M., Aref, Z. (2021). Relation between serum levels of Vitamin D and Immunoglobulin E in Allergic Rhinitis in Upper Egypt. EKB Journal Management System, 4(2), 69-75. doi: 10.21608/svuijm.2020.45265.1014
Aida A. Abdelmaksoud; Shamardan ES Bazeed; Mohamed F Alemam; Zaky Aref. "Relation between serum levels of Vitamin D and Immunoglobulin E in Allergic Rhinitis in Upper Egypt". EKB Journal Management System, 4, 2, 2021, 69-75. doi: 10.21608/svuijm.2020.45265.1014
Abdelmaksoud, A., Bazeed, S., Alemam, M., Aref, Z. (2021). 'Relation between serum levels of Vitamin D and Immunoglobulin E in Allergic Rhinitis in Upper Egypt', EKB Journal Management System, 4(2), pp. 69-75. doi: 10.21608/svuijm.2020.45265.1014
Abdelmaksoud, A., Bazeed, S., Alemam, M., Aref, Z. Relation between serum levels of Vitamin D and Immunoglobulin E in Allergic Rhinitis in Upper Egypt. EKB Journal Management System, 2021; 4(2): 69-75. doi: 10.21608/svuijm.2020.45265.1014

Relation between serum levels of Vitamin D and Immunoglobulin E in Allergic Rhinitis in Upper Egypt

SVU-International Journal of Medical Sciences
Article 7, Volume 4, Issue 2, August 2021, Page 69-75  XML PDF (212.38 K)
Document Type: Original research articles
DOI: 10.21608/svuijm.2020.45265.1014
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Authors
Aida A. Abdelmaksoud email orcid 1; Shamardan ES Bazeed2; Mohamed F Alemam3; Zaky Areforcid 1
1ENT Department, Faculty Of Medicine, South Valley University,Qena, Egypt.
2Tropical Medicine and Gastroenterology Department, Faculty Of Medicine, South Valley University,Qena, Egypt.
3Clinical and Chemical pathology Department, Faculty Of Medicine, South Valley University,Qena, Egypt.
Abstract
Objective: The object of this study is to evaluate the relation between 25- hydroxy cholecalciferol (vitamin D3) deficiency and allergic rhinitis by detecting level of 25-hydroxy cholecalciferol and Immunoglobulin E serum levels.
 Methods: This is a case-control study in which we compare two groups; group A included 69 patients diagnosed as allergic rhinitis (AR) and group B included 60 healthy individuals. Serum levels of cholecalciferol and serum levels of immunoglobulin (IgE) were assessed in all participants of both groups of this study.
Results: Serum level of 25- hydroxy cholecalciferol in group A (AR patients) was statistically significantly lower (mean ± SD: 14.2±8.04 ng/ml) than serum level of 25-hydroxy cholecalciferol in group B (21.1±8.2ng/ml). Also serum level of IGE in group A was markedly elevated in comparison to group B (494.4±61.7u/l) vs. (189.9±52.9u/l) with highly statistically significant difference (p-value < 0.001).
Conclusion: There is statistically significant relation between 25-hydroxy cholecalciferol  deficiency and allergic rhinitis; further studies must be done to assess the effect of Vitamin D3 therapy in allergic rhinitis.
Keywords
Allergic rhinitis; IgE; 25 hydroxy cholecalciferol
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