Prognosis of Unfractioned Heparin versus Low Molecular Weight Heparin in Pumlonary Embolism: Review Article
Binobaid, A., Alsaaid, M., Alasseri, I., Albareqi, B., Alabbas, K., Safi, M., Alasmari, A., Alhazmi, Y., Alaqaili, H., Khalaf, F., Shamlan, N., Al-Harthy, B., Alalwan, M., Alharban, A. (2017). Prognosis of Unfractioned Heparin versus Low Molecular Weight Heparin in Pumlonary Embolism: Review Article. EKB Journal Management System, 69(5), 2455-2458. doi: 10.12816/0041693
Abdullah Obaid Binobaid; Maan Ahmed Alsaaid; Ibrahim Ali I. Alasseri; Balgaith H. Albareqi; Kawther Abdulroof Alabbas; Meryem Safi; Ali Mohammed A. Alasmari; Yousef Mohammed Alhazmi; Haider Issa Alaqaili; Fatema Salman Hasan Salman Khalaf; Nareman Suliman Shamlan; Bashayer Ateya Al-Harthy; Mohannad Abdulrazzaq Alalwan; Adel Mushref Ali Alharban. "Prognosis of Unfractioned Heparin versus Low Molecular Weight Heparin in Pumlonary Embolism: Review Article". EKB Journal Management System, 69, 5, 2017, 2455-2458. doi: 10.12816/0041693
Binobaid, A., Alsaaid, M., Alasseri, I., Albareqi, B., Alabbas, K., Safi, M., Alasmari, A., Alhazmi, Y., Alaqaili, H., Khalaf, F., Shamlan, N., Al-Harthy, B., Alalwan, M., Alharban, A. (2017). 'Prognosis of Unfractioned Heparin versus Low Molecular Weight Heparin in Pumlonary Embolism: Review Article', EKB Journal Management System, 69(5), pp. 2455-2458. doi: 10.12816/0041693
Binobaid, A., Alsaaid, M., Alasseri, I., Albareqi, B., Alabbas, K., Safi, M., Alasmari, A., Alhazmi, Y., Alaqaili, H., Khalaf, F., Shamlan, N., Al-Harthy, B., Alalwan, M., Alharban, A. Prognosis of Unfractioned Heparin versus Low Molecular Weight Heparin in Pumlonary Embolism: Review Article. EKB Journal Management System, 2017; 69(5): 2455-2458. doi: 10.12816/0041693

Prognosis of Unfractioned Heparin versus Low Molecular Weight Heparin in Pumlonary Embolism: Review Article

The Egyptian Journal of Hospital Medicine
Article 15, Volume 69, Issue 5, October 2017, Page 2455-2458  XML PDF (219.95 K)
Document Type: Original Article
DOI: 10.12816/0041693
View on SCiNiTO View on SCiNiTO
Authors
Abdullah Obaid Binobaid email 1; Maan Ahmed Alsaaid2; Ibrahim Ali I. Alasseri3; Balgaith H. Albareqi4; Kawther Abdulroof Alabbas5; Meryem Safi6; Ali Mohammed A. Alasmari7; Yousef Mohammed Alhazmi8; Haider Issa Alaqaili9; Fatema Salman Hasan Salman Khalaf10; Nareman Suliman Shamlan11; Bashayer Ateya Al-Harthy12; Mohannad Abdulrazzaq Alalwan13; Adel Mushref Ali Alharban14
1Alfaisal University, Riyadh, Saudi Arabia
2Arabian Gulf University, Manama, Bahrain
3Majardah General Hospital, Abha, Saudi Arabia
4Primary Health Care, Al-Birk, Saudi Arabia
5Al Maarefa Colleges, Riyadh, Saudi Arabia.
6Ibn Sina National College, Jeddah, Saudi Arabia
7King Fahd Military Medical Complex, Dammam, Saudi Arabia
8Al Amal Mental Health Complex, Jeddah, Saudi Arabia
9Dammam Medical Complex, Dammam, Saudi Arabia
10October 6th University, Cairo, Egypt
11Batterjee Medical College
12Taif University, Taif, Saudi Arabia
13Imam Abdulrahman bin Faisal university, Dammam, Saudi Arabia.
14Primary Health Care, Abha, Saudi Arabia
Abstract
Anticoagulation is the mainstay treatment of pulmonary embolism. Using low molecular weight heparin versus unfractionated heparin remains a matter of debate. Objectives: the aim of this review is to study the prognosis of using low molecular weight versus unfractionated heparin in treatment of pulmonary embolism. Methods: PubMed and Cochrane library were searched for articles comparing the efficacy of low molecular weight heparin and unfractionated heparin in management of pulmonary embolism. Ten related results were selected for review. Results: Literatures studies indicated that low molecular weight heparin was effective in therapeutic treatment of acute sub-massive and massive pulmonary embolism. It was as effective as intravenous unfractionated heparin. It was not associated with higher risk of major, minor bleeding, or thrombocytopenia. Low molecular weight heparin was as effective as unfractionated heparin in prophylaxis of deep venous sinus thrombosis as well as pulmonary embolism.  Discussion: Low-molecular-weight heparin seemed to be as effective safe as intravenous unfractionated heparin for the treatment as well as prophylaxis of pulmonary embolism. It was also safe with no major bleeding risk or higher risk of thrombocytopenia. Conclusion: Both low molecular weight and unfractionated heparin had similar efficacy and safety in management of PE.
 
Keywords
pulmonary embolism; low molecular weight heparin; unfractionated heparin; Outcome
Statistics
Article View: 182
PDF Download: 230