The effect of non- surgical periodontal therapy on periostin level in the gingival crevicular fluid of type II diabetic patients with periodontitis
Morsy, S., Ali, N. (2020). The effect of non- surgical periodontal therapy on periostin level in the gingival crevicular fluid of type II diabetic patients with periodontitis. EKB Journal Management System, 66(Issue 4 - October (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)), 2261-2269. doi: 10.21608/edj.2020.36491.1177
Shaimaa Mohammed Morsy; Naema Goda Ali. "The effect of non- surgical periodontal therapy on periostin level in the gingival crevicular fluid of type II diabetic patients with periodontitis". EKB Journal Management System, 66, Issue 4 - October (Oral Medicine, X-Ray, Oral Biology & Oral Pathology), 2020, 2261-2269. doi: 10.21608/edj.2020.36491.1177
Morsy, S., Ali, N. (2020). 'The effect of non- surgical periodontal therapy on periostin level in the gingival crevicular fluid of type II diabetic patients with periodontitis', EKB Journal Management System, 66(Issue 4 - October (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)), pp. 2261-2269. doi: 10.21608/edj.2020.36491.1177
Morsy, S., Ali, N. The effect of non- surgical periodontal therapy on periostin level in the gingival crevicular fluid of type II diabetic patients with periodontitis. EKB Journal Management System, 2020; 66(Issue 4 - October (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)): 2261-2269. doi: 10.21608/edj.2020.36491.1177

The effect of non- surgical periodontal therapy on periostin level in the gingival crevicular fluid of type II diabetic patients with periodontitis

Egyptian Dental Journal
Article 9, Volume 66, Issue 4 - October (Oral Medicine, X-Ray, Oral Biology & Oral Pathology), October 2020, Page 2261-2269  XML PDF (396.22 K)
Document Type: Original Article
DOI: 10.21608/edj.2020.36491.1177
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Authors
Shaimaa Mohammed Morsy email orcid 1; Naema Goda Ali2
1oral medicine and periodontology department, faculty of dentistry, Suez Canal University
2oral medicine and periodontology, faculty of dentistry Suez canal university
Abstract
Abstract:
Background and Objective: periostin is a protein highly expressed within extracellular matrix of bone and periodontal ligament responsible for tissue integrity and play significant role in wound repair and bone remodeling. The present study designed to estimate the effectiveness of non surgical periodontal therapy (NSPT) on level of periostin in the gingival crevicular fluid (GCF) of diabetic patient with periodontitis.
Materials and Methods: 36 subjects were admitted in this study. The subjects allocated into 3 groups, group I involve 12 periodontally healthy subjects, group II involve 12 participants with periodontitis. Group III: involve 12 participants with periodontitis diagnosed with diabetes mellites type II. Group II and III were received conventional periodontal treatment scaling and root planning (S&RP). Clinical parameters: pocket depth (PD), clinical attachment loss (CAL), gingival index (GI), plaque index (PI) were measured and the GCF samples were gathered for assessment of periostin at baseline and at 3 months postoperatively.
Results: periostin level in the GCF were significantly increased in healthy subjects (P≤0.001) compared to those with diabetic patients with periodontitis and patients with periodontitis only. NSPT in group II and III resulted in significant increase (P≤0.001) in periostin level at 3 months postoperatively.
Conclusion: NSPT can significantly increase the level of periostin in the GCF of diabetic patients with periodontitis and those with periodontitis only. Moreover, periostin suggested to be inflammatory marker reliable for diagnosis and evaluation of the outcome of periodontal treatment.
Keywords
Keywords: periodontitis; diabetes mellites; gingival crevicular fluid; periostin; non- surgical periodontal therapy
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