Glasgow Coma Scale in Anticipation of Sepsis and Septic Shock: Review Article | ||||
The Egyptian Journal of Hospital Medicine | ||||
Article 17, Volume 69, Issue 6, October 2017, Page 2663-2666 PDF (223.03 K) | ||||
Document Type: Original Article | ||||
DOI: 10.12816/0042245 | ||||
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Authors | ||||
Mohammed Saeed M Alalawi ![]() | ||||
1Department of Emergency Medicine,Anak General Hospital, Anak, Saudi Arabia | ||||
2Department of Emergency Medicine, Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia | ||||
3Department of Emergency Medicine, King Saud University, Riyadh, Saudi Arabia | ||||
4Department of Emergency Medicine, Qassim University, Qassim, Saudi Arabia | ||||
5Department of Emergency Medicine, Jeddah University, Jeddah, Saudi Arabia | ||||
6Department of Emergency Medicine, Imam Muhammad ibn Saud Islamic University | ||||
7Department of Emergency Medicine,Taif University, Taif, Saudi Arabia | ||||
8Department of Emergency Medicine, King Faisal University, Hofuf, Saudi Arabia, | ||||
9Department of Emergency Medicine, Majmaah University, Al Majmaah, Saudi Arabia | ||||
10Department of Emergency Medicine, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland, | ||||
11Department of Emergency Medicine, Imam Abdulrahman bin Faisal University, Dammam | ||||
12Department of Emergency Medicine, Ibn Sina National College, Jeddah, Saudi Arabia | ||||
Abstract | ||||
Evaluation of level of consciousness has become essential for anticipation of sepsis and septic shock. Both the Sequential Organ Failure Assessment (SOFA) score and the quick SOFA score utilize the Glasgow Coma Score (GCS) for screening of sepsis. Objectives: the aim of this review is to determine and study the role of Glasgow coma score in anticipation of sepsis and septic shock. Methods: To achieve this aim, we have searched online database, namely PubMed and Cochrane Library for studies and review articles assessing the significance of assessment of Glasgow Coma Scale (GCS) for anticipating sepsis or septic shock. Thirteen appropriately-related studies were selected for review. Results: Disturbed sensorium was found to be a sensitive early indicator for sepsis, thus GCS is used for assessment of both the Sequential Organ Failure Assessment (SOFA) and quick SOFA scores qSOFA scores. Lower GCS scores were associated with high mortality rates. Discussion: Encephalopathy is an early sign of sepsis and septic shock. Glasgow Coma score (GCS) was a good indicator of neurological dysfunction evaluated by the SOFA and qSOFA scores. The use of GCS was also a predictor of mortality in patients with sepsis. Some researchers, however, reported that GCS was not the best tool for measuring brain dysfunction in sepsis. Conclusions: Glasgow coma score can anticipate sepsis and septic shock, and predict the outcome of sepsis. | ||||
Keywords | ||||
Glasgow Coma score; Sepsis; Septic shock | ||||
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