Green Synthesis of Zinc Oxide Nanoparticles Using Portulaca oleracea (Regla Seeds) Extract and Its Biomedical Applications | ||||
| Egyptian Journal of Chemistry | ||||
| Article 10, Volume 64, Issue 2, February 2021, Page 661-672 PDF (684.9 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejchem.2020.45592.2930 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Hend Y.G. Mohamed1; Eman Ismael2; Mahmoud M. Elaasser3; Mostafa M.H. Khalil   1
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| 1Chemistry Department, Faculty of Science, Ain Shams University | ||||
| 2Chemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, Egypt | ||||
| 3The Regional Center for Mycology and Biotechnology, Al-Azhar University, Cairo, Egypt | ||||
| Abstract | ||||
| In the present study, the biosynthesis of ZnONPs utilizing Portulaca oleracea seeds aqueous extract has been reported. The reported method is a green, plant-extract mediated and low-cost approach that is capable of synthesizing ZnONPs at pH 7 with heating at 60 oC for one hour. To demonstrate the efficiency of the capping bioorganic molecules on ZnO nanoparticles, a part of the product was dried at 60 oC (denoted ZnO-60) and the other part was annealed at 500 oC (denoted ZnO-500). Both synthesized ZnONPs was crystalline in nature and hexagonal in shape with an average size of 14 nm and 34.5 nm for ZnO-60 and ZnO-500, respectively, as evidenced by XRD and TEM analysis. The synthesized nanoparticles showed high antioxidant, good antibacterial activity, which has inhibited the growth of Helicobacter pylori (ATCC 700392) and Methicillin-Resistant Staphylococcus aureus bacteria and anticancer activity for HCT-116 cells with a higher efficiency of ZnO-60 than ZnO-500. | ||||
| Keywords | ||||
| Biosynthesis; Zinc oxide nanoparticles; Portulaca oleracea extract; antimicrobial; antioxidant; antitumor | ||||
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