Evaluation of Choroidal Thickness in Diabetic Macular Edema Using Spectral-Domain Optical Coherence Tomography Enhanced Depth Imaging Mode | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 18, Volume 69, Issue 6, October 2017, Page 2667-2674 PDF (452.04 K) | ||||
| DOI: 10.12816/0042246 | ||||
 View on SCiNiTO | ||||
| Author | ||||
| Mona Mohamad Aly | ||||
| Ophthalmology Department, Faculty of Medicine, Al-Azhar University | ||||
| Abstract | ||||
| Purpose: to evaluate the choroidal thickness (CH-T) and the central macular thickness (CMT) in eyes with diabetic macular edema (DME) and to detect if CH-T varies according to the type of DME. Patients and methods: One hundred forty two eyes of 96 patients were enrolled in the study. Eyes of diabetic patients with non-proliferative diabetic retinopathy (NPDR) with/without DME were evaluated. Eyes of normal subjects with no ocular or systemic diseases were included as a control group. The CMT and the underlying choroidal thickness were estimated using enhanced depth imaging mode of spectral-domain optical coherence tomography (EDI SD-OCT). CH-T thickness was measured at the subfoveal area and at an interval of 500 μm up to 1500 μm from the center of the fovea (nasal, temporal, superior and inferior). In eyes with DME, the type of DME was detected. Results: DME included cystoid DME (19 eyes), diffuse DME (27 eyes), and DME with serous retinal detachment (SRD) (23 eyes). 33 eyes with NPDR without DME and 40 non diabetic normal eyes were examined. Estimation of the choroidal thickness was performed and the subfoveal CH-T was thickest in the control group and significantly decreased in the diabetic groups especially with DME. The sub-foveal CH-T was 326±25.75 μm in the control group, 256.27±30.5 μm in NPDR without DME group, 210±23.96 μm in Cystoid DME group, 215.5±27.0 μm Diffuse DME group and 195.2±23.9 μm in DME with SRD group. The CMT was 238.75 ± 14.7 μm, 260.85 ± 24 μm, 530± 120.5 μm, 420.8± 101.6 μm and 506.60± 131.87 μm in the control group, NPDR without DME group, Cystoid DME, Diffuse DME and DME with SRD groups respectively. There was a statistically insignificant negative correlation between the subfoveal choroidal thickness and the CMT. Conclusion; there is an overall decrease in the CH-T in patients with NPDR and this thinning become more pronounced with the presence of diabetic macular edema. | ||||
| Keywords | ||||
| Diabetic Macular Edema; choroidal thickness; enhanced depth imaging; spectral-domain optical coherence tomography | ||||
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