Effect of Artificial Sweets on Neurologic Disorders | ||||
The Egyptian Journal of Hospital Medicine | ||||
Article 5, Volume 69, Issue 7, October 2017, Page 2783-2787 PDF (286.89 K) | ||||
Document Type: Original Article | ||||
DOI: 10.12816/0042565 | ||||
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Authors | ||||
Ali Malik Alahmed1; Mohammad Ehsan M Shokri2; Faris Ali Nasser Ayidh3; Amer Baraki Alotaib4; Tarnim Muhsen Alghamdi5; Faisal Barrak H Alziyadi6; Abdulsalam S. Alluhaydan7; Abdulwahab Malawi S Alshahrani3; Nora Faisal Alsaud8; Osama Abdulaziz M Gasem9; Abdulrhman Ebrahim A. Mughallis10; Albayyali,Tariq Hassan H11 | ||||
1University Of Dammam( Imam Abdulrahman Bin Faisal University), | ||||
2King Abdulaziz University Hospital | ||||
3King Khalid University | ||||
4King Abdullah Hospital-Bisha | ||||
5King Abdulaziz Hospital | ||||
6Klakh PHC,7- King Saud Medical City-Riyadh | ||||
7King Saud Medical City-Riyadh | ||||
8Alfaisal University | ||||
9King Abdulaziz University | ||||
10Jazan General Hospital | ||||
11Aljouf University | ||||
Abstract | ||||
Background: Sugar- and artificially-sweetened beverage consumption have been connected to cardio metabolic hazard factors, which rise the danger of cerebrovascular illness and dementia. Purpose: We studied whether sugar or artificially sweetened beverage intake was related with the prospective dangers of incident stroke or dementia. Materials and methods: We studied 361 members aged more than 45 years for incident stroke (mean age 61 [SD, 10] years; 163 men) and 185 participants aged >60 years for incident dementia (mean age 68 [SD, 7] years; 85 men). Beverage consumption was computed using a food-frequency questionnaire at cohort studies. We quantified latest consumption at investigation 7 and cumulative intake by averaging across examinations. Surveillance for incident events commenced at examination 7 and continued for 5 years. We observed 12 cases of incident stroke (10 ischemic) and 10 cases of incident dementia (8 consistent with Alzheimer’s disease). Results: After modifications for age, gender, education (for analysis of dementia), caloric consumption, diet feature, physical activity, and smoking, higher recent and higher cumulative consumption of artificially sweetened soft drinks were related with an increased risk of ischemic stroke, all-cause dementia, and Alzheimer’s disease dementia. When comparing day-to-day aggregate consumption to 0 per week (reference), the risk ratios were 2.87 (95% confidence interval, 1.24–6.89) for ischemic stroke and 2.91 (95% confidence interval, 1.15–6.99) for Alzheimer’s disease. Sugar-sweetened beverages were not associated with stroke or dementia. Conclusions: Artificially sweetened soft drink consumption was allied with a higher risk of stroke and dementia. | ||||
Keywords | ||||
Artificial Sweets; Soft Drinks; Dementia; stroke; sugar | ||||
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