Breast Cancer Staging and The Role of Radiology
Ghazwani, S., Rawah, M., Zarbah, J., Amoudi, A., Alyahya, F., H Aman, A., Abuazzah, R., Tallab, O., Alshammari, A., Akbar, A., Alharbi, A., Alsaad, F., Al Mehdar, A. (2017). Breast Cancer Staging and The Role of Radiology. EKB Journal Management System, 69(7), 2798-2803. doi: 10.12816/0042568
Salha Mofareh Ghazwani; Maram Adnan Rawah; Jaber Mohammed Zarbah; Abdulrahman Saleh Amoudi; Fatimah Hassan Alyahya; Abdulrahman Ahmed H Aman; Raed Fuad Ahmad Abuazzah; Omar Talal M Tallab; Amirah Ali Alshammari; Alaa Jamal A Akbar; Abdulrahman Abdulaziz Alharbi; Fatimah Nasser Alsaad; Amor Abdullah Al Mehdar. "Breast Cancer Staging and The Role of Radiology". EKB Journal Management System, 69, 7, 2017, 2798-2803. doi: 10.12816/0042568
Ghazwani, S., Rawah, M., Zarbah, J., Amoudi, A., Alyahya, F., H Aman, A., Abuazzah, R., Tallab, O., Alshammari, A., Akbar, A., Alharbi, A., Alsaad, F., Al Mehdar, A. (2017). 'Breast Cancer Staging and The Role of Radiology', EKB Journal Management System, 69(7), pp. 2798-2803. doi: 10.12816/0042568
Ghazwani, S., Rawah, M., Zarbah, J., Amoudi, A., Alyahya, F., H Aman, A., Abuazzah, R., Tallab, O., Alshammari, A., Akbar, A., Alharbi, A., Alsaad, F., Al Mehdar, A. Breast Cancer Staging and The Role of Radiology. EKB Journal Management System, 2017; 69(7): 2798-2803. doi: 10.12816/0042568

Breast Cancer Staging and The Role of Radiology

The Egyptian Journal of Hospital Medicine
Article 8, Volume 69, Issue 7, October 2017, Page 2798-2803  XML PDF (228.26 K)
Document Type: Original Article
DOI: 10.12816/0042568
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Authors
Salha Mofareh Ghazwani1; Maram Adnan Rawah2; Jaber Mohammed Zarbah3; Abdulrahman Saleh Amoudi4; Fatimah Hassan Alyahya5; Abdulrahman Ahmed H Aman6; Raed Fuad Ahmad Abuazzah7; Omar Talal M Tallab1; Amirah Ali Alshammari8; Alaa Jamal A Akbar9; Abdulrahman Abdulaziz Alharbi10; Fatimah Nasser Alsaad8; Amor Abdullah Al Mehdar11
1King Khalid University
2Jeddah Eye Hospital
3Najran University
4Madina Maternity and Children Hospital (MMCH)
5King Abdulaziz University in Jeddah
6Batterjee Medical College
7Taibah University
8Imam Abdulrahman Bin Faisal Hospital
9Ajyad Emergency Hospital, Makkah
10Umm Al-Qura University
11Ministry of Health
Abstract
Purpose: To Compare tomosynthesis to mammography, ultrasound, MRI, and histology for the detection and staging of BI-RADS 4–5 anomalies, as a function of breast composition, histology, size, and lesion location.
Materials and methods: 25 patients underwent tomosynthesis, MRI, mammography, and ultrasound. The diagnostic accuracy of the different examinations was compared.
Results: The sensitivities for detection were as follows: 92.7% for MRI, 80.5% for ultrasound, 75.6% for tomosynthesis, and 61% for mammography. Tomosynthesis improves the sensitivity of mammography (P = 0.0001), but not the specificity. The detection of multifocality and multicentricity was improved, but not significantly. Tomosynthesis identified more lesions than mammography in 10% of cases and improved lesion staging irrespective of the density, but was still inferior to MRI. The detection of ductal neoplasia was superior with tomosynthesis Compared to mammography (P = 0.016), but this was not the case with lobular cancer. The visualization of masses was improved with tomosynthesis (P = 0.00012), but not with  microcalcifications. Tomosynthesis was capable of differentiating lesions of all sizes, but the smaller lesions were easier to see. Lesion sizes measured with tomosynthesis, excluding the spicules, concurred with histological dimensions. Spicules lead to an overestimation of the size.
Conclusion: In our series, tomosynthesis found more lesions than mammography in 10% of patients, resulting in an adaption of the surgical plan.
 
Keywords
Breast; Tomosynthesis; Multifocality; Staging
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