The Role of Microbiota In The Occurrence of Non-Alcoholic Fatty Liver Disease
Shafik, N., ali, W., abdel baset, A., Farag, R., Noureldin, A., Orabi, O. (2021). The Role of Microbiota In The Occurrence of Non-Alcoholic Fatty Liver Disease. EKB Journal Management System, 25(1), 1-7. doi: 10.21608/smj.2020.42051.1194
Noha Saber Shafik; wafaa abdelghaffar ali; Asmaa Ahmed abdel baset; Radwa Mohammed Farag; Ahmed Nagah Noureldin; Osama Abbas Orabi. "The Role of Microbiota In The Occurrence of Non-Alcoholic Fatty Liver Disease". EKB Journal Management System, 25, 1, 2021, 1-7. doi: 10.21608/smj.2020.42051.1194
Shafik, N., ali, W., abdel baset, A., Farag, R., Noureldin, A., Orabi, O. (2021). 'The Role of Microbiota In The Occurrence of Non-Alcoholic Fatty Liver Disease', EKB Journal Management System, 25(1), pp. 1-7. doi: 10.21608/smj.2020.42051.1194
Shafik, N., ali, W., abdel baset, A., Farag, R., Noureldin, A., Orabi, O. The Role of Microbiota In The Occurrence of Non-Alcoholic Fatty Liver Disease. EKB Journal Management System, 2021; 25(1): 1-7. doi: 10.21608/smj.2020.42051.1194

The Role of Microbiota In The Occurrence of Non-Alcoholic Fatty Liver Disease

Sohag Medical Journal
Article 1, Volume 25, Issue 1, January 2021, Page 1-7  XML PDF (439.15 K)
Document Type: Original Article
DOI: 10.21608/smj.2020.42051.1194
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Authors
Noha Saber Shafik email 1; wafaa abdelghaffar ali2; Asmaa Ahmed abdel baset3; Radwa Mohammed Farag4; Ahmed Nagah Noureldin5; Osama Abbas Orabi6
1Medical microbiology , Faculty of Medicine, Sohag University, Egypt
2Forensic Medicine and Clinical toxicology faculty of medicine sohag university
3internal medicine, faculty of medicine, Sohag university, Sohag Egypt
4Clinical pathology, faculty of medicine, Sohag university
5Internal medicine, Faculty of medicine, Sohag univercity
6internal medicine, faculty of medicine
Abstract
Non- alcohol fatty liver disease (NAFLD) is the commest liver disease worldwide. In Western countries, prevalence between 20 and 30 % is reported among the adult population. Nutrition, excess eating food rich in saturated fats and high caloric food, along with decrease in eating vegetables, fruits, proteins, and 3-Fatty Acids are main contributors of NAFLD growth. Human beings have nearly one thousand bacterial organisms and several millions of bacteria, with 150-time more genes than the human genome colonizing in the human gasterointestinal tract. Lactobacillus, Peptoniphilus, Ruminococcus, Clostridium, and Eubacteria), Bacteroides, and Prevotella are the two main phyla in the human intestines. However, the components and presence of gut microbiota varies due to a high heterogeneity among people due to several factors as age, sex, general conditions, pregnancy, hormonal changes, travelling, infection, and drugs as chemotherapeutic agents or proton pump inhibitors. Our aim is to demonstrate the effect of gut microbiota in development of NAFLD.
Keywords
NAFLD; Gut Microbiota; Dysbiosis; Probiotics
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