Effect of Aging on the Histological Structure of the Duodenum Wall in Male Albino Rats | ||||
| SVU-International Journal of Medical Sciences | ||||
| Article 9, Volume 3, Issue 1, January 2020, Page 42-47 PDF (598.15 K) | ||||
| Document Type: Original research articles | ||||
| DOI: 10.21608/svuijm.2020.123754 | ||||
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| Authors | ||||
| Rania A. M. Ali* 1; Eman A. Abdelrahim1; Yasser A. G. Ahmed2; Soha M. Abdel-lateif2 | ||||
| 1Department of Histology, Faculty of Medicine , South Valley University, Qena, Egypt | ||||
| 2Department of Histology, Faculty of Veterinary Medicine, South Valley University, Qena, Egypt | ||||
| Abstract | ||||
| Background: Aging is a phenomenon that presents various alterations in neurochemical, behavioral and physiological processes. Objectives: This study aimed to evaluate the effect of aging on the histology of the duodenum of male albino rats. Materials and methods: thirty male albino rats will be divided into three groups according their age. Group A: Ten male albino rats (adult aged) at the age of 4 months. Group B: Ten albino rats (middle aged) at the age of 8months. Group C: Ten albino rats (old aged) at the age of 18 months. At the end of the experimental period, the animals were anaesthetized, then the duodenum was dissected out and specimens were processed for histological examination. Results: At the age of 4 months shrinkage in the core of the villus was recorded in the duodenum of rats. While deterioration in submucosal layer and deterioration in muscularis layer were seen in rats aged 8 months, in addition to congestion in mucosa. Many histological changes were observed in rats aged 18 months beginning from congestin in submucosa and detorioraion of muscle fibers in muscularis reaching congestion in mucosa and inflammation in crypts region and ending with necrosis in crypts and villi. Conclusion: From the present study it is concluded that, as age advances in male rats, a significant histological change involved the duodenum and at age 18 months the histological changes were more and obvious. | ||||
| Keywords | ||||
| Aging; duodenal wall; males; Rats | ||||
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