Novel Synthesis of Fused Pyrazolopyrimidines and C-Nucleosides of Thienopyrimidone with Expected Antimicrobial Activity | ||||
| Egyptian Journal of Chemistry | ||||
| Article 5, Volume 53, Issue 4, August 2010, Page 527-540 PDF (448.34 K) | ||||
| DOI: 10.21608/ejchem.2010.1247 | ||||
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| Abstract | ||||
| STARTING from thienopyrimidine hydrazine derivatives (1a,d) and (2b,c) a series of pyrazolopyrimidine derivatives has been synthesized. Also, some acyclic and cyclic C- nucleosides of thienopyrimidone (7-10) were prepared by treating compound 1a with aldoses. The prepared products showed antimicrobial activity. Structures of the new compounds were elucidated on the basis of their elemental analyses and spectral data. | ||||
| Keywords | ||||
| pyrazolopyrimidine; C-Nucleosides; NMR spectra; Mass spectra; Antibacterial and Antifungal Activities | ||||
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