Vitamin D Levels in Full-Term Neonates with Indirect Hyperbilirubinemia | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 18, Volume 81, Issue 5, October 2020, Page 2030-2035 PDF (443.69 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2020.124800 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Neveen T. Abed1; Farida F. Negm1; Enas S. Ahmad2; Heba A. Mohammed  1
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| 1Department of Pediatrics, Faculty of Medicine, Benha University, Egypt | ||||
| 2Department of Clinical and Chemical Pathology, Faculty of Medicine, Benha University, Egypt | ||||
| Abstract | ||||
| Background: Jaundice is a common clinical sign in neonatal medicine. Considering the different roles of vitamin D, its lower level may be correlated with neonatal jaundice. Objectives: This study aimed to demonstrate the relationship between serum vitamin D level and neonatal hyperbilirubinemia and to measure its level in their mothers. Subjects and methods: This case-control study was conducted on 90 neonates and their mothers, 60 neonates with hyperbilirubinemia in patients group and 30 healthy neonates age and sex matched in control group < /span>. Blood samples from neonates and their mothers were obtained and sent for laboratory estimation of 25-hydroxy vitamin D, calcium, magnesium, phosphorus, alkaline phosphatase and parathyroid hormone. Results: There is highly significant decrease of vitamin D levels among patients than controls, significant negative correlation between vitamin D levels and serum bilirubin in neonates and no significant difference regarding different laboratory parameters among their mothers. Conclusion: Decreased levels of vitamin D were significantly correlated with neonatal indirect hyperbilirubinemia so, low vitamin D can be included among risk factors for neonatal jaundice. | ||||
| Keywords | ||||
| Jaundice; Mothers; Neonatal; Vitamin D | ||||
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