EFFECT OF AROMATASE INHIBITOR THERAPY ON PREDICTED ADULT HEIGHT IN PREPUBERTAL BOYS WITH IDIOPATHIC SHORT STATURE | ||||
| Al-Azhar Journal of Pharmaceutical Sciences | ||||
| Article 5, Volume 51, Issue 1 - Serial Number 51, March 2015, Page 53-73 PDF (704.43 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ajps.2015.12492 | ||||
 View on SCiNiTO | ||||
| Author | ||||
| Thamar Mahmoud | ||||
| Department of Clinical Pharmacy, Faculty of Pharmacy, MISR University | ||||
| Abstract | ||||
| To investigate the effect of blocking estrogen biosynthesis with anastrozole, a potent aromatase inhibitor (AI) on growth and consequently predicted adult height (PAH) in boys with high estrogen level. Also, the effects of aromatase inhibition on gonadotropin secretion in boys during prepubertal phase. | ||||
| Keywords | ||||
| Growth hormone (GH); testosterone (T); estradiol (E2); aromatase inhibitor (AI); predicted adult height (PAH); idiopathic short stature (ISS) | ||||
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