PROSPECTIVE RANDOMIZED STUDY COMPARING LAPAROSCOPIC AND OPEN PARTIAL NEPHRECTOMY FOR TREATMENT OF RENAL TUMORS: SURGICAL AND FUNCTIONAL OUTCOMES
Tantaway, A., Eladl, M., Shoma, A., Ali, A. (2023). PROSPECTIVE RANDOMIZED STUDY COMPARING LAPAROSCOPIC AND OPEN PARTIAL NEPHRECTOMY FOR TREATMENT OF RENAL TUMORS: SURGICAL AND FUNCTIONAL OUTCOMES. EKB Journal Management System, 29(1.2), 228-234. doi: 10.21608/zumj.2020.46924.1978
Ahmed Wagdy Tantaway; Mahmoud Eladl; Ahmed Mamdouh Shoma; Ahmed Ragab Ali. "PROSPECTIVE RANDOMIZED STUDY COMPARING LAPAROSCOPIC AND OPEN PARTIAL NEPHRECTOMY FOR TREATMENT OF RENAL TUMORS: SURGICAL AND FUNCTIONAL OUTCOMES". EKB Journal Management System, 29, 1.2, 2023, 228-234. doi: 10.21608/zumj.2020.46924.1978
Tantaway, A., Eladl, M., Shoma, A., Ali, A. (2023). 'PROSPECTIVE RANDOMIZED STUDY COMPARING LAPAROSCOPIC AND OPEN PARTIAL NEPHRECTOMY FOR TREATMENT OF RENAL TUMORS: SURGICAL AND FUNCTIONAL OUTCOMES', EKB Journal Management System, 29(1.2), pp. 228-234. doi: 10.21608/zumj.2020.46924.1978
Tantaway, A., Eladl, M., Shoma, A., Ali, A. PROSPECTIVE RANDOMIZED STUDY COMPARING LAPAROSCOPIC AND OPEN PARTIAL NEPHRECTOMY FOR TREATMENT OF RENAL TUMORS: SURGICAL AND FUNCTIONAL OUTCOMES. EKB Journal Management System, 2023; 29(1.2): 228-234. doi: 10.21608/zumj.2020.46924.1978

PROSPECTIVE RANDOMIZED STUDY COMPARING LAPAROSCOPIC AND OPEN PARTIAL NEPHRECTOMY FOR TREATMENT OF RENAL TUMORS: SURGICAL AND FUNCTIONAL OUTCOMES

Zagazig University Medical Journal
Article 585, Volume 29, Issue 1.2, January 2023, Page 228-234  XML PDF (247.54 K)
Document Type: Original Article
DOI: 10.21608/zumj.2020.46924.1978
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Authors
Ahmed Wagdy Tantaway email orcid 1; Mahmoud Eladl2; Ahmed Mamdouh Shoma3; Ahmed Ragab Ali4
1Department of Urology, Faculty of Medicine, Zagazig University, Egypt
2Department of Urology Faculty of Medicine Zagazig University
3Department of Urology, Faculty of Medicine, Mansoura University, Egypt
4Department of Urology, Faculty of Medicine, Zagazig University, Zagazig, Egypt
Abstract
ABSTRACT
Background: The role of the open approach for partial nephrectomy is currently called into question by laparoscopy, although comparative studies on this issue are limited.
Objective: To compare surgical and renal functional outcomes after open partial nephrectomy (OPN) and laparoscopic partial nephrectomy (LPN).
Methods: This prospective randomized clinical study has been carried out at Urology department, Zagazig University from January 2017 till September 2020 on 35 patients candidates for partial nephrectomy, 17 patients in OPN and 18 patients in LPN.
Results: In total, 28 patients in both treatment groups complete the study. There was no statistical significant difference in age, gender, Body Mass Index (BMI), tumor size, tumor laterality and RENAL nephrometry score between both treatment groups. Significant differences were found between OPN and LPN regarding operative time (172.14±18.88 versus 148.93±31.88 min; P=0.027), estimate blood loss (252.86±70.32 versus 196.43±61.47 ml; P=0.032) and hospital stay (4.36±0.74 versus 3.14±1.1 days; P=0.002). Ischemia time was slightly higher in LPN (19.57±3.08 versus 17.79±2.15 min) without Significant difference (P=0.087). Positive safety margin was not significantly different between cases treated with OPN (1 case, 7%) and LPN (2 cases, 14%) (P=0.5). No cases developed local or distant recurrence during follow up period.
Conclusions: For cT1 renal tumors of low complexity, laparoscopic and open partial nephrectomy have comparable surgical and renal functional outcomes. LPN offers a strong alternative to OPN with shorter surgery time, less blood loss, and shorter hospital stay with quicker convalescence, with equivalent ischemia time compared to OPN.
Keywords
Renal tumors; laparoscopy; open partial nephrectomy; ischemia time
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