Anemia of Chronic Disease | ||||
The Egyptian Journal of Hospital Medicine | ||||
Article 9, Volume 69, Issue 8, October 2017, Page 2997-3002 PDF (318.88 K) | ||||
Document Type: Original Article | ||||
DOI: 10.12816/0042846 | ||||
View on SCiNiTO | ||||
Authors | ||||
Ayman Ali Alhboob1; Khuludyahyam. Khati2; SAMAHER Sahal Malibari3; Bariahyahya Drain4; Faisal Abdulmohsen Alhusayni5; Wafa Abdullah Alshamrani6; Abdullah Mohammad Almarzooq7; Nouf Mohammed Al Mutairi8; Duaamunir Alsafwani9; Ziyadwaleed Iskander4; Waleed Eid Alraddadi4; Aqeelasaad Alshubini10; Amal Ali Faheem4 | ||||
1Taiz University | ||||
2Batterjee Medical College for Sciences and Technology | ||||
3Umm Alqura University | ||||
4Ibn Sina National College for Health Sciences | ||||
5King Saud Bin Abdulaziz University for Health Sciences | ||||
6King Fahad Medical Military Hospital | ||||
7Imam Abdulrahman Bin Faisal University | ||||
8King Fahad Medical Military Complex in Dahran | ||||
9Arabian Gulf University | ||||
10Warsaw Medical University | ||||
Abstract | ||||
Introduction: Anemia of chronic disease has a widespread impact on patients with chronic disorders such as chronic inflammation, infection, malignancy etc. The pathophysiology behind it is largely due to involvement of hepcidin levels which are high as a result of the underlying chronic disorder, but negatively affects iron metabolism and erythropoiesis. Aim of the work: We tried to understand the pathogenesis, impact, diagnosis, and management of anemia due to chronic diseases. Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed and EMBASE from January 2001 to March 2017. The following search terms were used: anemia of chronic disease, anemia of inflammation, types of anemia, management of chronic anemia Conclusion: Since absolute treatment for the underlying chronic conditions are not available, various other modalities aimed at treating the anemia are developing. They include conventional and novel therapies. More researches must be done in order to manage the condition by treating the underlying cause, or for finding therapies with least side effects. | ||||
Keywords | ||||
anemia of chronic disease; anemia of inflammation; types of anemia; management of chronic anemia | ||||
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