CIRCULATING PATTERN OF RESPIRATORY VIRUSES, IN EGYPT, SEASON 2013-2014
Roshdy, W., Naguib, A., Elsayed, I., Shamikh, Y. (2020). CIRCULATING PATTERN OF RESPIRATORY VIRUSES, IN EGYPT, SEASON 2013-2014. EKB Journal Management System, 43(2), 237-253. doi: 10.21608/bfsa.2020.127419
Wael H. Roshdy; Amel M. Naguib; Ibrahim Elsayed; Yara I. Shamikh. "CIRCULATING PATTERN OF RESPIRATORY VIRUSES, IN EGYPT, SEASON 2013-2014". EKB Journal Management System, 43, 2, 2020, 237-253. doi: 10.21608/bfsa.2020.127419
Roshdy, W., Naguib, A., Elsayed, I., Shamikh, Y. (2020). 'CIRCULATING PATTERN OF RESPIRATORY VIRUSES, IN EGYPT, SEASON 2013-2014', EKB Journal Management System, 43(2), pp. 237-253. doi: 10.21608/bfsa.2020.127419
Roshdy, W., Naguib, A., Elsayed, I., Shamikh, Y. CIRCULATING PATTERN OF RESPIRATORY VIRUSES, IN EGYPT, SEASON 2013-2014. EKB Journal Management System, 2020; 43(2): 237-253. doi: 10.21608/bfsa.2020.127419

CIRCULATING PATTERN OF RESPIRATORY VIRUSES, IN EGYPT, SEASON 2013-2014

Bulletin of Pharmaceutical Sciences Assiut University
Article 14, Volume 43, Issue 2, December 2020, Page 237-253  XML PDF (588.74 K)
Document Type: Original Article
DOI: 10.21608/bfsa.2020.127419
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Authors
Wael H. Roshdyorcid 1; Amel M. Naguib2; Ibrahim Elsayed3; Yara I. Shamikhorcid 4
1PhD in Biochemistry and Molecular Virology, Head of Tissue Culture and Virus Isolation, Central Public Health Laboratories, CPHL, Ministry of Health, Cairo 11613, Egypt
2MSc in Clinical Pathology, Head of Virology Directorate, Central Public Health Laboratories, CPHL, Ministry of Health, Cairo 11613, Egypt
3Department of Biochemistry, Faculty of Science, Kafr Elsheikh University, Kafr Elsheikh 33784, Egypt
4Department of Microbiology and Immunology, Faculty of Pharmacy, Nahda University, Beni-Suef 62513, Egypt & Consultant, Virology Department, Egypt Centre for Research and Regenerative Medicine, ECRRM, Cairo 11517, Egypt
Abstract
Respiratory viruses causes lower and upper respiratory tract infections; LRTIs and URTIs. These infections are from the predominant causes of infections, especially in children and infants.
Objective: This study, provides the evidence of using modern techniques as the multiplex PCR method, as a helpful tool in identifying the circulating pattern of respiratory viruses, in Egypt, thus this could help in identifying and inventing new treatment and vaccines.
Subjects and methods: A number of 237 nasopharyngeal aspirates, were collected between December 2013 to November 2014, from 2 Egyptian fever hospitals, classified into 3 groups; group 1; 37 normal persons, group 2; 100 patients with LRTIs or pneumatic group and group 3; 100 patients with URTIs or common cold group. The results were then assayed using multiplex RT-PCR, in the Central Public Health Laboratories, CPHL, Ministry of Health, Cairo, Egypt.
Results: Respiratory viruses, were detected in 152 cases, where the human rhinovirus was the most prominent; 15.6%, followed by the respiratory syncytial virus, 10.5%, metapneumovirus; 13%, influenza-A (Flu-A); 6.3%, adenovirus (AdV); 5.9%, influenza-B (Flu-B); 5.4%, parainfluenza-3 (PIV-3); 4% and a percentage of 0.42% infection for parainfluenza-1 (PIV-1), parainfluenza-2 (PIV-2) and human bocavirus (HBoV). No infections with parainfluenza-4, enterovirus nor the coronaviruses were detected. Both season and age of the patients, affect the detection rate of the analysis.
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