The Effect of Cigarettes on Acute Pancreatitis Among Patients in Saudi Arabia
Alzahrani, A., Zaki O, H., Alsubhi, N., Alshehri, M., Alharthi, H., Alsahli, M., Alqurashi, F., Alghamdi, B., Khozam, S., Alsalbi, A., Albridi, A., Hassan H, A., Alburaidi, M. (2017). The Effect of Cigarettes on Acute Pancreatitis Among Patients in Saudi Arabia. EKB Journal Management System, 69(8), 3108-3114. doi: 10.12816/0042862
Amirah Abduallah M Alzahrani; Hariri, Mohammad Zaki O; Nahlah Ali Alsubhi; Mohammed Fayez Mohammed Alshehri; Helal Jarallah Alharthi; Muhannad Fahad W Alsahli; Faisal Menwer Alqurashi; Badr Saad Dhawi Alghamdi; Sabah Abdulrahman Khozam; Ali Ibrahim Ali Alsalbi; Ahmad Ibrahim M Albridi; Albayyali, Tariq Hassan H; Modhi Saleh Ibrahim Alburaidi. "The Effect of Cigarettes on Acute Pancreatitis Among Patients in Saudi Arabia". EKB Journal Management System, 69, 8, 2017, 3108-3114. doi: 10.12816/0042862
Alzahrani, A., Zaki O, H., Alsubhi, N., Alshehri, M., Alharthi, H., Alsahli, M., Alqurashi, F., Alghamdi, B., Khozam, S., Alsalbi, A., Albridi, A., Hassan H, A., Alburaidi, M. (2017). 'The Effect of Cigarettes on Acute Pancreatitis Among Patients in Saudi Arabia', EKB Journal Management System, 69(8), pp. 3108-3114. doi: 10.12816/0042862
Alzahrani, A., Zaki O, H., Alsubhi, N., Alshehri, M., Alharthi, H., Alsahli, M., Alqurashi, F., Alghamdi, B., Khozam, S., Alsalbi, A., Albridi, A., Hassan H, A., Alburaidi, M. The Effect of Cigarettes on Acute Pancreatitis Among Patients in Saudi Arabia. EKB Journal Management System, 2017; 69(8): 3108-3114. doi: 10.12816/0042862

The Effect of Cigarettes on Acute Pancreatitis Among Patients in Saudi Arabia

The Egyptian Journal of Hospital Medicine
Article 25, Volume 69, Issue 8, October 2017, Page 3108-3114  XML PDF (322.1 K)
Document Type: Original Article
DOI: 10.12816/0042862
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Authors
Amirah Abduallah M Alzahrani1; Hariri, Mohammad Zaki O2; Nahlah Ali Alsubhi3; Mohammed Fayez Mohammed Alshehri4; Helal Jarallah Alharthi5; Muhannad Fahad W Alsahli6; Faisal Menwer Alqurashi7; Badr Saad Dhawi Alghamdi8; Sabah Abdulrahman Khozam4; Ali Ibrahim Ali Alsalbi9; Ahmad Ibrahim M Albridi4; Albayyali, Tariq Hassan H10; Modhi Saleh Ibrahim Alburaidi11
1King Abualziz Hospital
2Public Health Center, Makkah
3Ibn Sina National College
4King Khalid University
5University of Warmia and Mazury, Poland
6Al Imam Abdulrahman Alfaisal Hospital in Riyadh
7Umm Alqura University
8Buljurashi Psychiatric Hospital
9Taibah University
10Al-Jouf University
11Qassim University
Abstract
Background and purpose: Questions remain unclear about the association of smoking status and the development of acute pancreatitis (AP). We performed a meta-analysis of observational studies to explore this association. Materials and Methods: A computerized literature search was performed in MEDLINE and EMBASE through October 15, 2016. We also searched the reference lists of pertinent articles. We used a rand om-effects model to calculate the summary relative risks (SRRs) and their corresponding 95% confidence intervals (CIs).
Results: A total of 8 observational studies (4 case control and 4 prospective cohort/nested case control studies) were identified. Compared with never smokers, the summary RR estimates were 1.49 (95% CI, 1.29-1.78) for ever smokers, 1.69 (95% CI, 1.42-2.21) for current smokers, and 1.19 (95% CI, 1.11-1.52) for former smokers. Smoking is found to be a potential risk factor for alcohol use, idiopathic factors and drugs related AP, but not for gallstone related AP, in the ever and current smokers. A dose response effect of tobacco use on the risk was ascertained: current smokers had a 40% (95% CI, 30%-50%) increased risk of AP for every additional 10 cigarettes per day.
Conclusion: The current analysis suggests that smokers have an elevated risk of AP development. Further studies, however, are warranted before definitive conclusions can be drawn.
 
 
Keywords
pancreatitis; cigarettes; Smoking; Meta-Analysis
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