The effect of cigarette smoking on choroidal vasculature measured by Optical Coherence Tomography Angiography (OCTA)
Saber, E., SAIF, M., Saeed, M. (2021). The effect of cigarette smoking on choroidal vasculature measured by Optical Coherence Tomography Angiography (OCTA). EKB Journal Management System, 4(Geriatric Ophthalmology), 1-18. doi: 10.21608/niles.2020.46466.1039
Ebtsam Saber; Mohamed Yasser Sayed SAIF; Moustafa Abd-Elnaby Saeed. "The effect of cigarette smoking on choroidal vasculature measured by Optical Coherence Tomography Angiography (OCTA)". EKB Journal Management System, 4, Geriatric Ophthalmology, 2021, 1-18. doi: 10.21608/niles.2020.46466.1039
Saber, E., SAIF, M., Saeed, M. (2021). 'The effect of cigarette smoking on choroidal vasculature measured by Optical Coherence Tomography Angiography (OCTA)', EKB Journal Management System, 4(Geriatric Ophthalmology), pp. 1-18. doi: 10.21608/niles.2020.46466.1039
Saber, E., SAIF, M., Saeed, M. The effect of cigarette smoking on choroidal vasculature measured by Optical Coherence Tomography Angiography (OCTA). EKB Journal Management System, 2021; 4(Geriatric Ophthalmology): 1-18. doi: 10.21608/niles.2020.46466.1039

The effect of cigarette smoking on choroidal vasculature measured by Optical Coherence Tomography Angiography (OCTA)

NILES journal for Geriatric and Gerontology
Article 1, Volume 4, Geriatric Ophthalmology, April 2021, Page 1-18  XML PDF (1.29 MB)
Document Type: Original Article
DOI: 10.21608/niles.2020.46466.1039
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Authors
Ebtsam Saber email 1; Mohamed Yasser Sayed SAIForcid 2, 3; Moustafa Abd-Elnaby Saeedorcid 4
1Ophthalmology department, Faculty of medicine ,BeniSuef university , Egypt
2Ophthalmology department , Faculty of Medicine , Beni-Suef University
3NILES , Beni-Suef University
4Department of Ophthalmology, Beni-Suef University
Abstract
Background: Cigarette smoking has been associated with low blood velocity of ophthalmic artery, while systolic blood pressure has been positively correlated with velocities in the ophthalmic artery and the central retinal artery. These effects are the result of interaction of nicotine-induced peripheral vasoconstriction and vasodilation caused by carbon monoxide in smokers. OCTA is a novel, noninvasive scanning technology which allow visualizing of the retinal and choroidal circulation. It permits assessing the retinal vasculature layer by layer and allows physicians to take images of the deep capillary plexus with no dye injection.
Methods: retrospective case control study included 100 participants (50 smokers and 50 healthy nonsmokers) recruited from Ophthalmology Department in Beni -Suef University Hospital. Participants were equally divided into two groups: Group (1): Included 50 smokers otherwise healthy. Group (2): Included 50 normal subjects (nonsmokers) used as control. Both groups underwent OCTA study.
Results: A highly significant statistical difference between both groups regarding smoking duration, while age and gender were of no significant. No statistical difference between both groups regarding perfusion within retinal layers between both groups as recorded in whole image. Age, IOP and neovascularization were positively, correlated with duration of smoking, perfusion and choroidal thicknesses in all areas were negatively correlated with duration of smoking.
Conclusion: We did not find a significant difference in choroidal blood flow, vessel density, or choroidal thickness measurements between the study and control groups in a chronic period. We also noticed that OCTA is a good new noninvasive procedure for imaging choroidal circulation.
Keywords
Choroidal circulation; OCTA; smoking effect; Optical coherence tomography angiography
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