PCR Genetic Expression of Interleukin 37 in the Eutopic and Ectopic Endometrium of Women with Endometriosis
Abbas, A., EL-Desouky, S., Allam, I., Mohamed, D., Abou –Gamrah, A. (2020). PCR Genetic Expression of Interleukin 37 in the Eutopic and Ectopic Endometrium of Women with Endometriosis. EKB Journal Management System, 81(7), 2410-2415. doi: 10.21608/ejhm.2020.132889
Ahmed Mohamed Abbas; Sayeda Ibrahim EL-Desouky; Ihab Fouad Serag Eldin Allam; Deena A Mohamed; Amgad Alsaid Abou –Gamrah. "PCR Genetic Expression of Interleukin 37 in the Eutopic and Ectopic Endometrium of Women with Endometriosis". EKB Journal Management System, 81, 7, 2020, 2410-2415. doi: 10.21608/ejhm.2020.132889
Abbas, A., EL-Desouky, S., Allam, I., Mohamed, D., Abou –Gamrah, A. (2020). 'PCR Genetic Expression of Interleukin 37 in the Eutopic and Ectopic Endometrium of Women with Endometriosis', EKB Journal Management System, 81(7), pp. 2410-2415. doi: 10.21608/ejhm.2020.132889
Abbas, A., EL-Desouky, S., Allam, I., Mohamed, D., Abou –Gamrah, A. PCR Genetic Expression of Interleukin 37 in the Eutopic and Ectopic Endometrium of Women with Endometriosis. EKB Journal Management System, 2020; 81(7): 2410-2415. doi: 10.21608/ejhm.2020.132889

PCR Genetic Expression of Interleukin 37 in the Eutopic and Ectopic Endometrium of Women with Endometriosis

The Egyptian Journal of Hospital Medicine
Article 19, Volume 81, Issue 7, October 2020, Page 2410-2415  XML PDF (332.62 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2020.132889
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Authors
Ahmed Mohamed Abbas; Sayeda Ibrahim EL-Desouky* ; Ihab Fouad Serag Eldin Allam; Deena A Mohamed; Amgad Alsaid Abou –Gamrah
Abstract
Background: In endometriosis, there is a chronic immune and inflammatory reaction.
Objective: To study the PCR genetic expression of interleukin 37 in the eutopic and ectopic endometrium of women with endometriosis in comparison with controls.
Patient and Methods: Forty-six patients were included in the study. Twenty-three women diagnosed as endometriosis and twenty-three women diagnosed as free of endometriosis were subjected to laparoscopy for any other gynecological cause. Interleukin 37 gene expression was studied in ectopic and eutopic endometrium using polymerase chain reaction.
Results: Ectopic endometrium expressed high levels of mRNA compared to eutopic endometrium in endometriosis patients. Eutopic endometrium of endometriosis patients expressed high levels of mRNA compared to eutopic endometrium of controls.
Conclusion: The finding of high mRNA produced in endometrial tissue suggests that interleukin 37 may be important in the chronic inflammation occurring during endometriosis.
Keywords
Endometriosis; PCR Genetic Expression; Interleukin 37
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