The Relationship between Abdominal Aortic Calcification and Cardiac Abnormalities in Hemodialysis Patients | ||||
The Egyptian Journal of Hospital Medicine | ||||
Article 29, Volume 68, Issue 1, July 2017, Page 1059-1068 PDF (601.15 K) | ||||
Document Type: Original Article | ||||
DOI: 10.12816/0038209 | ||||
View on SCiNiTO | ||||
Authors | ||||
Tamer Mohamed Ragb1; Ahmad AlaaEldin Ahmad Saad1; Moneir Osman Amin Abd Elaal2; Abdellah Nazeer Yassin3; ALSayed Mohamed Rashed1 | ||||
1Departments of Internal medicine Faculty of Medicine, Al Azhar university, Cairo, Egypt | ||||
2Departments of Internal CardiologyFaculty of Medicine, Al Azhar university, Cairo, Egypt | ||||
3Departments of Internal RadiologyFaculty of Medicine, Al Azhar university, Cairo, Egypt | ||||
Abstract | ||||
Background: Abdominal aortic calcification (AAC) is a marker of subclinical atherosclerotic disease and an independent predictor of subsequent vascular morbidity and mortality. Aim of the work: This study was conducted to investigate the association of abdominal aortic calcification with cardiac abnormalitiesin hemodialysispatient (HD). Methods: This cross-sectionalobservational study wasperformed on 90 patients (50 males and 40 females)with chronic kidney disease, stage 5 (CKD)of varying etiologies from hemodialysis unit at Al-Hussein UniversityHospital. They wereundergoing regularhemodialysis for more than 6 monthes.Laboratory investigations were done including liver function tests, kidney function tests,complete blood count (CBC),C-reactive protein (CRP), fasting and random blood glucose,lipid profile, calcium, phosphorus,calcium phosphate productandparathormone(PTH).In addition, Echocardiography and X-ray plain radiography were determined. Results: Out of 90 HD patients, 37 patients (41.1 %) had valvular calcification, all of them (41.1 %) had aortic valve calcifications and AAC score exceeded 6. Only 7 patients (7.8%)had mitral valve calcifications. Moreover, cases with mitral valve calcifications had aortic valve calcification and AAC score above 12. Seven patients (7.8 %) had mildaortic regurgitation (AR)and 4 patients (4.44%) had aortic stenosis. Conclusion: AAC precedes the occurrence of cardiac abnormalities in HD patients and has been shown to have significant prognostic significance for cardiovascular events and mortality. | ||||
Keywords | ||||
abdominal; calcification; Cardiac; Kidney disease; chronic; Radiography | ||||
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