Role of TRIM Proteins in Inflammatory Skin Diseases | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 28, Volume 81, Issue 7, October 2020, Page 2462-2467 PDF (525.24 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2020.133965 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Rehab Monir Samaka; Mohamed Ahmed Basha; Dalia El Beih | ||||
| Abstract | ||||
| Background: Despite the advance in treatment modalities of wide range inflammatory skin diseases, tripartite motif- containing (TRIM) proteins are expected to become a potential therapeutic target for prevention and treatment of dermatological disorders. Objective: Studying the role of TRIM proteins in inflammatory skin diseases. Material and Methods: We searched the PubMed and Google scholar databases for relevant studies that evaluated the expression of TRIM proteins in inflammatory skin diseases. Study Selection: All the studies were independently assessed for inclusion. They were included if they fulfilled the following criteria: published in English language, published in peer-reviewed journals, focused on the role of TRIM proteins in inflammatory skin diseases. The initial search presented 30 articles of which 8 met the inclusion criteria. The articles studied the effect of role of TRIM proteins in inflammatory skin diseases. Data Synthesis: Comparisons were made by structured review with the results tabulated. Conclusion: We concluded that TRIM proteins play an important role in inflammatory skin diseases development, prognosis and treatment. | ||||
| Keywords | ||||
| Tripartite motif proteins; TRIM proteins; Inflammatory Skin diseases; Psoriasis; Atopic dermatitis | ||||
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