Correlations between Serum Levels of Interleukin-2 and Different Symptoms of Schizophrenic Disorders | ||||
| Benha Journal of Applied Sciences | ||||
| Article 18, Volume 5, Issue 1 part (2), January 2020, Page 305-309 PDF (798.44 K) | ||||
| Document Type: Original Research Papers | ||||
| DOI: 10.21608/bjas.2020.135414 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| M.M. El Hamady; A.M. Matta; Sh.T. El-Bakry; M.F. Ebrahim | ||||
| Neuropsychiatry Dept., Faculty of Medicine, Benha Univ., Benha, Egypt | ||||
| Abstract | ||||
| Schizophrenia (SZ) is a chronic psychiatric disorder characterized by positive (e.g., hallucinations and delusions), negative (e.g., apathy and impaired motivation), and cognitive symptoms (e.g., poor performance in executive functions and attention). Interleukin-2( IL-2) has been one of the most frequently studied cytokines in schizophrenia. Several studies have pointed to a potential role of IL-2 in SZ,with most studies reporting altered peripheral levels of IL-2 when compared with healthy controls. The aim of this work is to determine serum level of interlukin-2 in a sample of schizophrenic patients. Also to compare the serum levels of IL-2 in schizophrenic patients and healthy controls and to investigate a possible correlation with positive and negative symptoms of. This analytic (case control) study included thirty patients with schizophrenia and a similar number of normal healthy individuals as control group. Both groups were subjected to a semi structured interview, SCID, PANSS and serum level of IL-2. | ||||
| Keywords | ||||
| Interleukin-2; Schizophrenia; Immunology | ||||
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