1,5 Anhydroglucitol Evaluation as Glycemic Control Parameter of Diabetes Mellitus in Pregnancy | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 34, Volume 68, Issue 3, July 2017, Page 1527-1532 PDF (473.76 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.12816/0039699 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Helmy M. Elsayed; Mohammed EM. Ibrahim; Mohammed SL El Safty; Samar MM Salim | ||||
| Department of Obstetrics and Gynecology,Faculty of Medicine, Ain Shams University | ||||
| Abstract | ||||
| Background: 1,5-Anhydroglucitol (1,5-AG) provides a reliable opportunity to assess the frequency and extent of intermittent hyperglycemic episodes. Aim of the Work: this study aimed to evaluate an alternative parameter to monitor blood glucose in pregnancies complicated with diabetes mellitus by studying the relationship between 1,5 Anhydroglucitol and self-monitoring of blood glucose level in pregnant women complicated with diabetes mellitus. Patients and Methods: this cross-sectional study with retrospective data was conducted on seventy pregnant women known to have pre-gestational or gestational diabetes mellitus attending Ain Shams University Maternity Hospital fulfilling the inclusion criteria of pre-gestational or gestational diabetes mellitus according to the criteria of the American Diabetes Association. Results: this study revealed a highly significant negative correlation between MMG (mean maximum glycemia) and 1,5 AG (r: -0.817, p-value: <0.001), also pre prandial blood glucose level (r: -0.500, p-value: <0.001) and a negative correlation and highly significant was found between post prandial blood glucose level and 1,5 AG (r: -0.640, p-value: <0.001). Conclusion: 1,5-AG is better than HbA1c as a tool for monitoring the glucose profile in pregnancies complicated by diabetes mellitus especially for the hyperglycemic episodes. Recommendations: as majority of interpretations for utility of 1,5-AG in pregnancy are based on scanty few clinical data so there is a scope of potential possibilities for its use in pregnancy and continuous research may allow its new applications and usefulness in pregnancy in the future. | ||||
| Keywords | ||||
| 1; 5 Anhydroglucitol; Glycemic Control Parameter; Diabetes mellitus; Pregnancy | ||||
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