Effect of pre-emptive epidural Mg sulphate versus dexmedetomidine on postoperative analgesia requirement after open abdominal surgeries
Ismaiel, W., Salman, O., Abdellatif, A., Omar, M. (2023). Effect of pre-emptive epidural Mg sulphate versus dexmedetomidine on postoperative analgesia requirement after open abdominal surgeries. EKB Journal Management System, 6(2), 181-186. doi: 10.21608/svuijm.2021.54255.1056
Wafaa Abd-Elnasser Ismaiel; Osama Hamdy Salman; Ahmed Fathy Abdellatif; Mohamed Ahmed Omar. "Effect of pre-emptive epidural Mg sulphate versus dexmedetomidine on postoperative analgesia requirement after open abdominal surgeries". EKB Journal Management System, 6, 2, 2023, 181-186. doi: 10.21608/svuijm.2021.54255.1056
Ismaiel, W., Salman, O., Abdellatif, A., Omar, M. (2023). 'Effect of pre-emptive epidural Mg sulphate versus dexmedetomidine on postoperative analgesia requirement after open abdominal surgeries', EKB Journal Management System, 6(2), pp. 181-186. doi: 10.21608/svuijm.2021.54255.1056
Ismaiel, W., Salman, O., Abdellatif, A., Omar, M. Effect of pre-emptive epidural Mg sulphate versus dexmedetomidine on postoperative analgesia requirement after open abdominal surgeries. EKB Journal Management System, 2023; 6(2): 181-186. doi: 10.21608/svuijm.2021.54255.1056

Effect of pre-emptive epidural Mg sulphate versus dexmedetomidine on postoperative analgesia requirement after open abdominal surgeries

SVU-International Journal of Medical Sciences
Article 16, Volume 6, Issue 2, July 2023, Pages 181-186    PDF (306.2 K)
Document Type: Original research articles
DOI: 10.21608/svuijm.2021.54255.1056
Authors
Wafaa Abd-Elnasser Ismaiel* 1; Osama Hamdy Salman1; Ahmed Fathy Abdellatif2; Mohamed Ahmed Omar3
1Department of anaesthesia& ICU, Faculty of Medicine, South Valley University, Qena, Egypt..
2Department of anaesthesia& ICU, Faculty of Medicine, South Valley University, Qena, Egypt
3Department of general surgery, Faculty of Medicine, South valley University, Qena, Egypt
Abstract
Background: epidural approach is used to provide anaesthesia and analgesia (pain relief) in abdominal surgeries.
Objectives: To estimate total cumulative dose of post-operative rescue analgesia &
to estimate time to 1st post-operative analgesic request.
Patients and methods: A prospective randomized double blind observational study. Conducted in Qena university hospital, South Valley University, Qena, Egypt. The study was conducted on sixty patients (ASA I or II) scheduled for major abdominal surgeries with general anesthesia combined with epidural anesthesia were included. Their ages ranged between 25 and 60 years old.
Results: Regarding assessment of post-operative pain by visual analogue scale (VAS) we find that there was statistically significant difference between the three groups 24hour post-operative. there were significant difference (P<0.05) about the time to reach VAS 4 , that the time to reach VAS 4 in dexmedetomidine group is longer than the time to reach VAS 4 in Mg sulphate group than the time to reach VAS 4 in control group.
Conclusion: Epidural Dexmedetomedine and Epidural Magnesium sulphate are safe in open abdominal surgeries and effectively reducing postoperative pain with longer duration of analgesia in Dexmedetomedine group.
Keywords
Epidural approach; Magnesium sulfate; Dexmedetomedine
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