Determination of Lipid Peroxidation , Lipid profile and Vitamins A, E in Type ll Diabetes Mellitus
Hussien, S., Altoum, A., Sadig, I. (2015). Determination of Lipid Peroxidation , Lipid profile and Vitamins A, E in Type ll Diabetes Mellitus. EKB Journal Management System, 7(1), 113-119. doi: 10.21608/eajbsc.2015.13708
Salah Eldin O. Hussien; AbdElgadir A. Altoum; Isam, M. Sadig. "Determination of Lipid Peroxidation , Lipid profile and Vitamins A, E in Type ll Diabetes Mellitus". EKB Journal Management System, 7, 1, 2015, 113-119. doi: 10.21608/eajbsc.2015.13708
Hussien, S., Altoum, A., Sadig, I. (2015). 'Determination of Lipid Peroxidation , Lipid profile and Vitamins A, E in Type ll Diabetes Mellitus', EKB Journal Management System, 7(1), pp. 113-119. doi: 10.21608/eajbsc.2015.13708
Hussien, S., Altoum, A., Sadig, I. Determination of Lipid Peroxidation , Lipid profile and Vitamins A, E in Type ll Diabetes Mellitus. EKB Journal Management System, 2015; 7(1): 113-119. doi: 10.21608/eajbsc.2015.13708

Determination of Lipid Peroxidation , Lipid profile and Vitamins A, E in Type ll Diabetes Mellitus

Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology
Article 11, Volume 7, Issue 1, September 2015, Page 113-119  XML PDF (338.31 K)
Document Type: Original Article
DOI: 10.21608/eajbsc.2015.13708
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Authors
Salah Eldin O. Hussien1; AbdElgadir A. Altoum2; Isam, M. Sadig3
1College of Applied Medical Sciences,Department of Medical Laboratory Technology, University of Taibah, Kingdom of Saudi Arabia
2College of Medical Laboratory Science Department of Clinical Chemistry, University of Sciences and Technology
3College of Medical Laboratory Science, Department of Clinical Chemistry, Omdurman Islamic University
Abstract
Background: Type 2 diabetes is the commonest form of diabetes and associated with multiple metabolic derangements that result in the excessive production of reactive oxygen species (ROS) and oxidative stress, the aim of present study was to Determined of Lipid Per oxidation , Lipid profile and Vitamins A, E In Sudanese with Type ll Diabetes Mellitus. Methodology:100 healthy subject were control group with mean FBS= 5.61m. mol/L,. The age ranged from (25-78) years old. The mean age average was50.2(years). Results: shows significant raised of the means of the plasma levels of malondialehyde, fasting plasma glucose, cholesterol, LDL, triglyceride, and HbA1c of the test group when compared with healthy control group subjects, whereas the means of the plasma levels of antioxidant vitamins (A, E),and HDL showed significant reduction when compared with that of control groupsignificant difference when compared with healthy subjects.
Conclusion: The present study shows that significant lipoprotein abnormalities in type 2 diabetic patients when compared with healthy subjects. The increased level of serum MDA and lower level of serum vitamin E clearly shows that diabetic patients was exposed to an increased oxidative stress via lipid peroxidation.
Keywords
Vitamins A; E Type ll Diabetes Mellitus
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