Serum Interleukin 19 in Patients with Alopecia Areata | ||||
| Benha Journal of Applied Sciences | ||||
| Article 5, Volume 5, Issue 6 part (2), September 2020, Page 187-189 PDF (564.58 K) | ||||
| Document Type: Original Research Papers | ||||
| DOI: 10.21608/bjas.2020.137139 | ||||
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| Authors | ||||
| A.A. Ebrahim; A.I. Mustafa; W.A. Abd El-Haleem; A.E. Salah | ||||
| Dermatology, Venereology and Andrology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt | ||||
| Abstract | ||||
| Alopecia areata (AA) is a typical ailment influencing the analgen period of the hair follicles. Interleukin (IL)- 19 is an individual from an IL-10 subfamily which additionally incorporates IL-20, IL-22 and IL-24. It normally shows as restricted, all around differentiated patches of going bald. It might present as single or different patches. The point of this examination was to survey the degree of serum of IL-19 in patients with AA to assess its part in AA pathogenesis and its conceivable connection with seriousness of the illness. Case control study included 30 patients experiencing AA notwithstanding 30 obviously sound people of coordinated age and sex as a benchmark group. Analysis of AA was made based on clinical discoveries and the seriousness of the sores will be evaluated by Severity of Alopecia Tool (SALT) score. The serum IL-19 levels estimated by chemical connected immunosorbent examine (ELISA). We found that all out AA bunch indicated fundamentally higher serum IL-19 when contrasted with control gathering. Higher IL-19 was essentially connected with dynamic cases. Likewise, it expanded steadily with seriousness. Something else, no noteworthy affiliations were found with respect to IL-19 level as indicated by sexual orientation, family ancestry, beginning, course, assortment, repeat and past treatment in AA gathering. | ||||
| Keywords | ||||
| Alopecia areata; Interleukin-19 | ||||
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