Behaviour of 4,6-Diaryl-2(1H) pyrimidine-2-thiones Towards Some Electrophiles and Nucleophiles | ||||
| Egyptian Journal of Chemistry | ||||
| Article 2, Volume 54, Issue 1, February 2012, Page 17-34 PDF (481 K) | ||||
| DOI: 10.21608/ejchem.2011.1377 | ||||
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| Abstract | ||||
| 4,6-DIARYl-1,2-dihydro-2(1H)-pyrimidine-2-thiones (1a,b) were ….used for the synthesis of several new pyrimidine derivatives. They were further subjected to hetero ring anellation affording isoxazolo [4,5-d] thiazolo [2,3-a] pyrimidine (5,6) and isoxazolo [4,5-d] thiazino [2,3-a] pyrimidines (11,12) . Biological evaluation of some of the prepared compounds revealed promising antimicrobial activity. | ||||
| Keywords | ||||
| Pyrimidinethione; Pyrimidothiazine; Thiazolopyrimidine and Antimicrobial activity | ||||
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