EFFECT OF ANTHELMINTICS DRUGS ON BIOCHEMICAL CHARACTERISTICS OF BULL FRIESIAN FROZEN SEMEN | ||||
| Delta Journal of Science | ||||
| Article 10, Volume 36, Issue 3, December 2013, Page 212-223 PDF (848.77 K) | ||||
| Document Type: Research and Reference | ||||
| DOI: 10.21608/djs.2013.139779 | ||||
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| Authors | ||||
| Ghada, A. Tabl1; Nabila, I. El-Desouki1; Alaa, E. B. Zeidan2; Mohamed, A. Tag El-Deen2; Rabab, A. Kamel3 | ||||
| 1Department of Zoology, Faculty of Science, Tanta University, Egypt | ||||
| 2Animal Production Research Institute, Dokki, Giza, Egypt | ||||
| 3Department of Physics, Faculty of Science and Arts in Al-Ardah, Gazan University, Kingdom of Saudi Arabia | ||||
| Abstract | ||||
| Three different antihelmintic drugs were used in the present study (ivermectin, levamisole and albendazole) on Friesian bulls .The animals were divided into four groups (control untreated group, ivermectin, levamisole, and albendazole treated groups, respectively). The drugs used at two doses with 8 weeks intervals between first and second one at 200μg/kg, 7.5mg/kg and 10mg/kg, respectively. Semen samples were collected for 8th weeks after each dose. Biochemical semen characteristics were estimated. The bulls treated with ivermectin showed significant increase in semen- ejaculate volume, sperm- cells concentration (x109 / ml), total sperm output ejaculate (x109 / ml), alkaline phosphatase (ALP) and prostatic acid phosphatase (ACP) activities in seminal plasma, seminal plasma total proteins, globulin, urea and zinc concentration; while significantly decreased seminal plasma alanine-aminotransferase (ALT), aspartate-aminotranferase (AST), and sodium were reported. The bulls treated with levamisole showed significant increase in semen-ejaculate volume, total sperm output/ejaculate, ALP and prostatic ACP activities in seminal plasma, seminal plasma total proteins, globulin, urea and zinc concentrations; while significantly decreased seminal plasma ALT, AST, and sodium were recorded. In contrary, the bulls treated with albendazole were significantly decreased semenejaculate volume, sperm motility, seminal plasma total proteins, globulin, creatinine and calcium. Also, it showed significant increase in seminal plasma enzymes activity (ALT, AST and ALP) and zinc concentrations. It is interest to note that different anthelmintics treatment used in this study didn’t affect significantly in seminal plasma albumin and total ACP activity. In conclusion: Ivermectin treatment improved semen qualities by increasing seminal volume and concentration. Anthelmintics treatment with levamisole should be used carefully under control during breeding season. Albendazole treatment should be avoided because its harmful effect in semen by decreasing semen-ejaculate volume, sperm motility, seminal plasma total proteins, globulin and increasing seminal plasma aminotransferase enzymes activity. | ||||
| Keywords | ||||
| Anthelmintics; Bulls; Frozen Semen; Physical & Chemical estimation | ||||
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