Clinical and radiographic evaluation of open flap debridement with or without Nanocrystalline Hydroxyapatite bone graft in management of periodontal intrabony defects
Elbattawy, W., Ahmed, D. (2021). Clinical and radiographic evaluation of open flap debridement with or without Nanocrystalline Hydroxyapatite bone graft in management of periodontal intrabony defects. EKB Journal Management System, 67(Issue 1 - January (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)), 433-446. doi: 10.21608/edj.2020.51002.1361
Weam Elbattawy; Dina Ahmed. "Clinical and radiographic evaluation of open flap debridement with or without Nanocrystalline Hydroxyapatite bone graft in management of periodontal intrabony defects". EKB Journal Management System, 67, Issue 1 - January (Oral Medicine, X-Ray, Oral Biology & Oral Pathology), 2021, 433-446. doi: 10.21608/edj.2020.51002.1361
Elbattawy, W., Ahmed, D. (2021). 'Clinical and radiographic evaluation of open flap debridement with or without Nanocrystalline Hydroxyapatite bone graft in management of periodontal intrabony defects', EKB Journal Management System, 67(Issue 1 - January (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)), pp. 433-446. doi: 10.21608/edj.2020.51002.1361
Elbattawy, W., Ahmed, D. Clinical and radiographic evaluation of open flap debridement with or without Nanocrystalline Hydroxyapatite bone graft in management of periodontal intrabony defects. EKB Journal Management System, 2021; 67(Issue 1 - January (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)): 433-446. doi: 10.21608/edj.2020.51002.1361

Clinical and radiographic evaluation of open flap debridement with or without Nanocrystalline Hydroxyapatite bone graft in management of periodontal intrabony defects

Egyptian Dental Journal
Article 14, Volume 67, Issue 1 - January (Oral Medicine, X-Ray, Oral Biology & Oral Pathology) - Serial Number 3, January 2021, Page 433-446  XML PDF (993.95 K)
Document Type: Original Article
DOI: 10.21608/edj.2020.51002.1361
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Authors
Weam Elbattawy email orcid 1; Dina Ahmedorcid 2
1Lecturer, Department of Oral Medicine and Periodontology, Faculty of Dentistry, Cairo University, Cairo, Egypt.
2Associate Professor, Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Cairo University, Cairo, Egypt
Abstract
Abstract:

Background:
Nanocrystalline hydroxyapatite (n-HA) bone graft could improve proliferation and differentiation of periodontal ligament fibroblasts. The osteoconductive and biomimetic properties incorporated into the early stage of human physiological bone turnover assumed that deposition of these molecules promoted early osteogenesis in and around Nano Bone.
Methods:
20 periodontitis patients with intra-bony defects participated in this clinical trial and treated with either open flap debridement (OFD) alone as control group or OFD and n-HA bone graft as intervention group. Clinical outcomes included plaque index (PI), gingival index (GI), probing depth (PD), clinical attachment level (CAL) and gingival recession (GR). Bone defect area (BDA) was measured by digital periapical radiographs and linear measurements were used to calculate the radiographic bone fill. Measurements at baseline and 6-months postoperatively were subjected to statistical analysis.
Results:
Both OFD and OFD with n-HA bone substitute resulted in statistically significant improvement in all clinical and radiographic parameters from baseline to 6 months. But no significant difference was observed between both groups. After 6 months, OFD showed 2.4(±0.5)mm PD reduction and 1.2(±0.8)mm CAL gain, while n-HA group showed 3.2(±1.1)mm PD reduction and 2.7(±1.3)mm CAL gain. The BDA was reduced by 1.7(±1)mm2 with OFD and by 3.4(±2.2)mm2 in n-HA group.
Conclusion:
Both OFD and OFD with n-HA showed significant reduction in clinical and radiographic outcomes after 6 months with no statistically significant difference between them.
Clinical relevance:
Both treatment modalities are successful procedures for treating intrabony defects
Keywords
Nanocrystalline Hydroxyapatite bone substitute; open flap debridement; intrabony defects; periodontal regeneration
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