Does Leishmania infantum Use Degenerating Midgut Cells of The Vector as A Nutrient Source?
El - Sattar, S., Dillon, R., El - Sawaf, B. (2018). Does Leishmania infantum Use Degenerating Midgut Cells of The Vector as A Nutrient Source?. EKB Journal Management System, 10(1), 21-28. doi: 10.21608/eajbse.2018.14457
Sanaa A. El - Sattar; Rod J. Dillon; Bahira M. El - Sawaf. "Does Leishmania infantum Use Degenerating Midgut Cells of The Vector as A Nutrient Source?". EKB Journal Management System, 10, 1, 2018, 21-28. doi: 10.21608/eajbse.2018.14457
El - Sattar, S., Dillon, R., El - Sawaf, B. (2018). 'Does Leishmania infantum Use Degenerating Midgut Cells of The Vector as A Nutrient Source?', EKB Journal Management System, 10(1), pp. 21-28. doi: 10.21608/eajbse.2018.14457
El - Sattar, S., Dillon, R., El - Sawaf, B. Does Leishmania infantum Use Degenerating Midgut Cells of The Vector as A Nutrient Source?. EKB Journal Management System, 2018; 10(1): 21-28. doi: 10.21608/eajbse.2018.14457

Does Leishmania infantum Use Degenerating Midgut Cells of The Vector as A Nutrient Source?

Egyptian Academic Journal of Biological Sciences, E. Medical Entomology & Parasitology
Article 3, Volume 10, Issue 1, June 2018, Page 21-28  XML PDF (916.08 K)
Document Type: Original Article
DOI: 10.21608/eajbse.2018.14457
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Authors
Sanaa A. El - Sattar1; Rod J. Dillon2; Bahira M. El - Sawaf3
1Research & Training Center on Vectors of Diseases, Ain Shams University, Cairo, Egypt
2Imperial College, London, UK.
3Faculty of Science, Ain Shams University, Cairo, Egypt
Abstract
Ultrastructural evidence from Phlebotomus
langeroni experim-entally infected with Leishmania infantum
was found from day 4 postinfection to support the hypothesis that shed midgut
cells act as an important nutrient source for the parasite. Thirteen areas of
degenerating cells occurred in 12 sections of infected flies compared to none
in complementary controls 8 days post-infection. Parasites penetrated
degenerating cells in 7 of 30 flies sectioned (days 8-11 post-infection), and
were frequently found packed around shed cells in the gut lumen. No
melanisation was observed, suggesting that although higher cell turnover was
probably induced by parasites they did not destroy intact cells.
Keywords
sand flies; Phlebotomus langeroni; Leishmania infantum; experimental infection; Ultrastructure
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